TY - JOUR AU - Dubois, Andre T1 - Spiral Bacteria in the Human Stomach: The Gastric Helicobacters T2 - Emerging Infectious Disease journal PY - 1995 VL - 1 IS - 3 SP - 79 SN - 1080-6059 AB - During the past decade, Helicobacter pylori has become recognized as one of the most common human pathogens, colonizing the gastric mucosa of almost all persons exposed to poor hygienic conditions from childhood. It also is often found, albeit with a lower frequency, in groups of high socioeconomic status. H. pylori causes chronic active gastritis and is a major factor in the pathogenesis of duodenal ulcers and, to a lesser extent, gastric ulcers. In addition, the presence of this bacterium is now recognized as a risk factor for gastric adenocarcinoma and lymphoma. Nevertheless, most infections appear without clinical consequences. In this second decade of intensive research, it is important to understand why H. pylori is sometimes a dangerous pathogen, and to determine how it can be eradicated in those at highest risk for severe disease. KW - United States DO - 10.3201/eid0103.950302 UR - https://wwwnc.cdc.gov/eid/article/1/3/95-0302_article ER - End of Reference