TY - JOUR AU - Beasley, David W.C. AU - Davis, C. Todd AU - Estrada-Franco, Jose AU - Navarro-Lopez, Roberto AU - Campomanes-Cortes, Arturo AU - Tesh, Robert B. AU - Vasilakis, Nikos AU - Barrett, Alan D.T. T1 - Genome Sequence and Attenuating Mutations in West Nile Virus Isolate from Mexico T2 - Emerging Infectious Disease journal PY - 2004 VL - 10 IS - 12 SP - 2221 SN - 1080-6059 AB - The complete genome sequence of a Mexican West Nile virus isolate, TM171-03, included 46 nucleotide (0.42%) and 4 amino acid (0.11%) differences from the NY99 prototype. Mouse virulence differences between plaque-purified variants of TM171-03 with mutations at the E protein glycosylation motif suggest the emergence of an attenuating mutation. KW - West Nile virus KW - arbovirus KW - flavivirus KW - Mexico KW - genome sequence KW - dispatch DO - 10.3201/eid1012.040647 UR - https://wwwnc.cdc.gov/eid/article/10/12/04-0647_article ER - End of Reference