TY - JOUR
AU - Albrich, Werner C.
AU - Monnet, Dominique L.
AU - Harbarth, Stephan
T1 - Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes
T2 - Emerging Infectious Disease journal
PY - 2004
VL - 10
IS - 3
SP - 514
SN - 1080-6059
AB - We correlated outpatient antibiotic use with prevalence of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP), macrolide-resistant S. pneumoniae (MRSP), and macrolide-resistant S. pyogenes (MRGAS) in 20 countries. Total antibiotic use was correlated with PNSP (r = 0.75; p < 0.001), as was macrolide use with MRSP (r = 0.88; p < 0.001) and MRGAS (r = 0.71; p = 0.004). Streptococcal resistance is directly associated with antibiotic selection pressure on a national level.
KW - antibiotics
KW - drug resistance, microbial
KW - epidemiology
KW - Streptococcus pneumoniae
KW - Streptococcus pyogenes
DO - 10.3201/eid1003.030252
UR - https://wwwnc.cdc.gov/eid/article/10/3/03-0252_article
ER - End of Reference