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Volume 11, Number 11—November 2005
Research

Neutralizing Antibody Response and SARS Severity

Mei-Shang Ho*, Wei-Ju Chen*, Hour-Young Chen†, Szu-Fong Lin†, Min-Chin Wang†, Jiali Di†, Yen-Ta Lu‡, Ching-Lung Liu‡, Shan-Chwen Chang§, Chung-Liang Chao¶, Chwan-Chuen King§, Jeng-Min Chiou*, Ih-Jen Su#, and Jyh-Yuan Yang†Comments to Author 
Author affiliations: *Academia Sinica, Taipei, Taiwan; †Center for Disease Control, Taipei, Taiwan; ‡Taipei Mackay Memorial Hospital, Taipei, Taiwan; §National Taiwan University, Taipei, Taiwan; ¶Taipei Hospital, Taipei, Taiwan; #National Health Research Institutes, Taipei, Taiwan

Main Article

Table 2

Comparison of SARS antibody results of ELISA and neutralization assay*

ELISA† Neutralizing antibody‡
Positive Negative
Positive 207 1
Negative 10 206
Total 217 207

*SARS, severe acute respiratory syndrome; ELISA, enzyme-linked immunosorbent assay.
†Reagents were supplied by Thomas Ksiazek, Centers for Disease Control and Prevention, Atlanta, GA, USA (2 reagents).
‡Using ELISA as the reference assay, the sensitivity of the neutralizing antibody (NT) test = 99.5%, the specificity of neutralizing antibody = 95.4%.

Main Article

Page created: February 17, 2012
Page updated: February 17, 2012
Page reviewed: February 17, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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