Volume 11, Number 11—November 2005
Dispatch
West Nile Virus Epidemic, Northeast Ohio, 2002
Table 1
Seroprevalence | No. positive/no. tested | Weighted % (95% CI) |
---|---|---|
Overall | 34/1,209 | 1.9 (0.8–4.6) |
Age-specific | ||
5–17 y | 4/168 | 6.5 (4.3–9.5) |
18–64 y | 25/790 | 1.3 (0.4–4.5)† |
>65 y | 5/219 | 1.4 (0.4–4.5)‡ |
Strata-specific | ||
More human illnesses reported; higher MIR(stratum 1)§¶ | 16/463 | 2.5 (0.6–9.2) |
Fewer human illnesses reported; varying MIR (stratum 2)# | 7/453 | 1.5 (0.2–4.4) |
No human illnesses reported; varying MIR (stratum 3)** | 11/293 | 3.3 (0.4–23.9) |
*WNV, West Nile virus; CI, confidence interval; MIR, minimum infection rate.
†Significant difference between 5- to 17-year-old and 18- to 64-year-old patients (p<0.02).
‡Significant difference between 5- to 17-year-old and >65-year-old patients (p<0.01).
§Reference 9.
¶Stratum 1 included neighborhoods with at least 9 reported human cases, a WNV case rate >4.5/10,000, and mosquito MIR >15/1,000.
#Stratum 2 included neighborhoods with at least 1 reported human case, a WNV case rate <4.5/10,000, and varying levels of MIR (0–54/1,000).
**Stratum 3 included neighborhoods with no known human cases and varying levels of MIR.
References
- Sejvar JJ, Haddad MB, Tierney BC, Campbell GL, Marfin AA, Van Gerpen JA, Neurologic manifestations and outcome of West Nile virus infection. JAMA. 2003;290:511–5. DOIPubMedGoogle Scholar
- Centers for Disease Control and Prevention. Investigations of West Nile virus infections in recipients of blood transfusions. MMWR Morb Mortal Wkly Rep. 2002;51:973–4.PubMedGoogle Scholar
- Centers for Disease Control and Prevention. Intrauterine West Nile virus infection—New York, 2002. MMWR Morb Mortal Wkly Rep. 2002;51:1135–6.PubMedGoogle Scholar
- Centers for Disease Control and Prevention. Possible West Nile virus transmission to an infant through breast-feeding—Michigan, 2002. MMWR Morb Mortal Wkly Rep. 2002;51:877–8.PubMedGoogle Scholar
- Petersen LR, Hayes EB. Westward ho?—The spread of West Nile virus. N Engl J Med. 2004;351:2257–9. DOIPubMedGoogle Scholar
- O'Leary D, Marfin A, Montgomery S, Kipp A, Lehman J, Biggerstaff B, The epidemic of West Nile virus in the United States, 2002. Vector Borne Zoonotic Dis. 2004;4:61–70. DOIPubMedGoogle Scholar
- Mostashari F, Bunning ML, Kitsutani PT, Singer DA, Nash D, Cooper MJ, Epidemic West Nile encephalitis, New York, 1999: results of a household-based seroepidemiological survey. Lancet. 2001;358:261–4. DOIPubMedGoogle Scholar
- Tsai T, Popovici F, Cernescu C, Campbell G, Nedelcu N. West Nile encephalitis epidemic in southeastern Romania. Lancet. 1998;352:767–71. DOIPubMedGoogle Scholar
- Le CT. A new estimator for infection rates using pools of variable size. Am J Epidemiol. 1981;114:132–6.PubMedGoogle Scholar
- Centers for Disease Control and Prevention. Serosurveys for West Nile virus infection—New York and Connecticut counties, 2000. JAMA. 2001;285:727–8. DOIPubMedGoogle Scholar
- Prince HE, Hogrefe WR. Detection of West Nile virus (WNV)–specific immunoglobulin M in a reference laboratory setting during the 2002 WNV season in the United States. Clin Diagn Lab Immunol. 2003;10:764–8.PubMedGoogle Scholar
- Martin DA, Muth DA, Brown T, Johnson AJ, Karabatsos N, Roehrig JT. Standardization of immunoglobulin M capture enzyme-linked immunosorbent assays for routine diagnosis of arboviral infections. J Clin Microbiol. 2000;38:1823–6.PubMedGoogle Scholar
- Johnson AJ, Martin DA, Karabatsos N, Roehrig JT. Detection of anti-arboviral immunoglobulin G by using a monoclonal antibody-based capture enzyme-linked immunosorbent assay. J Clin Microbiol. 2000;38:1827–31.PubMedGoogle Scholar
- Cochran W. 9A.7. In: Sampling techniques. 3rd ed. New York: Wiley; 1977.
- Hayes EB, O'Leary DR. West Nile virus infection: a pediatric perspective. Pediatrics. 2004;113:1375–81. DOIPubMedGoogle Scholar
Page created: February 17, 2012
Page updated: February 17, 2012
Page reviewed: February 17, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.