Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 11, Number 8—August 2005
Research

Influenza A (H3N2) Outbreak, Nepal

Luke T. Daum*†Comments to Author , Michael Shaw‡, Alexander I. Klimov‡, Linda C. Canas*, Elizabeth A. Macias*, Debra Niemeyer*, James K. Chambers†, Robert Renthal†, Sanjaya K. Shrestha§, Ramesh P. Acharya¶, Shankar P. Huzdar¶, Nirmal Rimal¶, Khin S. Myint#, and Philip Gould*
Author affiliations: *Air Force Institute for Operational Health, Brooks City Base, San Antonio, Texas; †University of Texas, San Antonio, Texas; ‡Centers for Disease Control and Prevention, Atlanta, Georgia; §Walter Reed/Armed Forces Research Institute of Medical Sciences Research Unit-Nepal, Kathmandu, Nepal; ¶Association of Medical Doctors of Asia-Nepal, Kathmandu, Nepal; #US Army Medical Component of the Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand

Main Article

Table 2

Unique hemagglutinin amino acid substitutions from influenza virus isolates obtained during July 2004 influenza outbreak in southeast Nepal compared with 5 vaccine strains*

Virus strain Amino acid position
145
Glycosylation site adjacent to antibody site A 155
Fujian-like lineage amino acid substitution 156
Fujian-like lineage amino acid substitution 189
Antibody site B 226
Antibody site D 227
Antibody site D
A/Nepal Consensus/04† N T H N I P
A/Fujian/411/02 K T H S V S
A/Wyoming/3/03 K T H S I S
A/Wellington/1/04 K T H N V P
A/California/7/04 N T H N I P
A/Panama/2007/99 K H Q S V S

*N, asparagine; T, threonine; H, histidine; I, isoleucine; P, proline; K, lysine; S, serine; V, valine; Q, glutamine.
†Consensus sequence derived from a multiple sequence protein alignment of 26 HA1 hemagglutinin sequences from Nepal.

Main Article

Page created: April 23, 2012
Page updated: April 23, 2012
Page reviewed: April 23, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external