Volume 11, Number 9—September 2005
Multidrug-resistant Tuberculosis Detection, Latvia
|Line probe rpoB gene mutation results||BACTEC 460 System
*N = 88; Includes 86 Mycobacterium tuberculosis isolates from BACTEC plus 2 isolates that grew on Löwenstein-Jensen media.
†Compared to results from BACTEC drug susceptibility testing, the line probe assay had a sensitivity of 91% (95% confidence interval [CI] 83–99) and a specificity of 96% (95% CI 92–100). The positive predictive value of the line probe rpoB mutation result for rifampin resistance was 94% (95% CI 88–100), and the negative predictive value was 96% (95% CI 92–100).