TY - JOUR AU - Grijalva, Carlos AU - Craig, Allen AU - Dupont, William AU - Bridges, Carolyn AU - Schrag, Stephanie AU - Iwane, Marika AU - Schaffner, William AU - Edwards, Kathryn AU - Griffin, Marie T1 - Estimating Influenza Hospitalizations among Children T2 - Emerging Infectious Disease journal PY - 2006 VL - 12 IS - 1 SP - 103 SN - 1080-6059 AB - Although influenza causes more hospitalizations and deaths among American children than any other vaccine-preventable disease, deriving accurate population-based estimates of disease impact is challenging. Using 2 independent surveillance systems, we performed a capture-recapture analysis to estimate influenza-associated hospitalizations in children in Davidson County, Tennessee, during the 2003–2004 influenza season. The New Vaccine Surveillance Network (NVSN) enrolled children hospitalized with respiratory symptoms or fever and tested them for influenza. The Tennessee Emerging Infections Program (EIP) identified inpatients with positive influenza diagnostic test results through review of laboratory and infection control logs. The hospitalization rate estimated from the capture-recapture analysis in children <5 years of age was 2.4 per 1,000 (95% confidence interval 1.8–3.8). When NVSN estimates were compared with capture-recapture estimates, NVSN found 84% of community-acquired cases, EIP found 64% of cases in which an influenza rapid test was performed, and the overall sensitivity of NVSN and EIP for influenza hospitalizations was 73% and 38%, respectively. KW - Influenza KW - children KW - surveillance KW - epidemiologic methods KW - research KW - United States DO - 10.3201/eid1201.050308 UR - https://wwwnc.cdc.gov/eid/article/12/1/05-0308_article ER - End of Reference