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Volume 12, Number 11—November 2006
Dispatch

Fatal Avian Influenza A H5N1 in a Dog

Thaweesak Songserm*, Alongkorn Amonsin†, Rungroj Jam-on*, Namdee Sae-Heng*, Nuananong Pariyothorn†, Sunchai Payungporn†, Apiradee Theamboonlers†, Salin Chutinimitkul†, Roongroje Thanawongnuwech†, and Yong Poovorawan†Comments to Author 
Author affiliations: *Kasetsart University, Nakorn Pathom, Thailand; †Chulalongkorn University, Bangkok, Thailand

Main Article

Table

Genetic comparison of 8 gene segments of the H5N1 influenza virus isolated from the dog's lung (KU-08) to those of H5N1 isolates from Thailand*

GD-1: goose (1996)‡ CU-K2:chicken (Jan 04)§ SP-33: human (Jan 04)¶ Ti-1: tiger (Jan 04)# KU-02: cat (Jan 04)** CU-23: chicken (Jul 04)†† CU-T3: tiger (Oct 04)‡‡ CK-160: chicken (Oct 05)§§ NK-165: human (Dec 05)¶¶ QH-65: goose (Jun 05)##
HA 46–1623 96.0 97.1 99.0 99.6 99.6 99.6 100.0 99.2 98.9 96.8
NA 28–1296 91.6 99.3 99.3 99.5 99.5 99.9 100.0 98.5 98.8 97.2
M 1–801 96.1 99.5 99.6 99.4 99.9 99.9 100.0 99.4 99.3 98.1
NS 37–789 68.5 99.0 99.2 99.3 99.5 99.3 100.0 99.1 99.0 96.4
NP 58–1428 92.6 99.7 99.7 99.6 99.6 99.8 99.9 99.1 99.1 98.1
PA 28–2118 93.5 99.4 99.3 99.5 99.4 99.5 99.7 99.2 98.8 97.7
PB1 67–2229 93.4 99.6 99.8 99.8 99.8 99.9 100.0 99.1 98.8 97.9
PB2 88-2220 94.0 99.4 99.3 99.4 99.7 99.8 99.8 98.9 98.9 97.5

*HA, hemagluttinin; NA, neuraminadase; M, matrix; NS, nonstructural; NP,nucleoprotein; PA, polymerase A; PB, polymerase basic protein.
†A/dog/Thailand-Suphanburi/KU-08/04 (DQ530170–7).
‡A/Goose/Guangdong/1/96 (AF144300–7).
§A/chicken/Nakorn-Patom/Thailand/CU-K2/04 (AY590567- 8, AY590578–82, AY551934).
¶A/Thailand/SP-33/04 (AY555152–3, AY627893–8).
#A/tiger/Suphanburi/Thailand/Ti-1/04 (AY646167–74).
**A/cat/Thailand/KU-02/04 (DQ236077–84).
††A/chicken/Ayutthaya/Thailand/CU-23/04 (AY770991- AY7709918).
‡‡A/tiger/Thailand/CU-T3/04 (AY907672–3, AY842935–6, AY972547–50).
§§A/chicken/Thailand/Kanchanaburi/CK-160/05 (DQ334757–64).
¶¶A/Thailand/NK165/05 (DQ372591–8).
##A/Bar-headed Goose/Qinghai/65/05 (DQ095622, DQ095642, DQ095662, DQ095682, DQ095702, DQ095722, DQ095742, DQ095762).

*HA, hemagluttinin; NA, neuraminadase; M, matrix; NS, nonstructural; NP,nucleoprotein; PA, polymerase A; PB, polymerase basic protein.
†A/dog/Thailand-Suphanburi/KU-08/04 (DQ530170–7).
‡A/Goose/Guangdong/1/96 (AF144300–7).
§A/chicken/Nakorn-Patom/Thailand/CU-K2/04 (AY590567- 8, AY590578–82, AY551934).
¶A/Thailand/SP-33/04 (AY555152–3, AY627893–8).
#A/tiger/Suphanburi/Thailand/Ti-1/04 (AY646167–74).
**A/cat/Thailand/KU-02/04 (DQ236077–84).
††A/chicken/Ayutthaya/Thailand/CU-23/04 (AY770991- AY7709918).
‡‡A/tiger/Thailand/CU-T3/04 (AY907672–3, AY842935–6, AY972547–50).
§§A/chicken/Thailand/Kanchanaburi/CK-160/05 (DQ334757–64).
¶¶A/Thailand/NK165/05 (DQ372591–8).
##A/Bar-headed Goose/Qinghai/65/05 (DQ095622, DQ095642, DQ095662, DQ095682, DQ095702, DQ095722, DQ095742, DQ095762).

Main Article

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