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Volume 12, Number 11—November 2006
Perspective

Prophylaxis and Treatment of Pregnant Women for Emerging Infections and Bioterrorism Emergencies

Joanne Cono*Comments to Author , Janet D. Cragan*, Denise J. Jamieson*, and Sonja A. Rasmussen*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 1

US Food and Drug Administration use-in-pregnancy drug classifications (21 CFR 201.57)

Category Description
A Well-controlled studies in humans fail to demonstrate fetal risk.
B Human risk is relatively unlikely because of negative results in animal studies and no human studies, or positive results in animal studies and negative results in human studies.
C Human fetal risk is unknown; positive results in animal studies (or no animal studies) and no human studies.
D Evidence of human fetal risk; however, drug benefits may outweigh risks.
X Positive results in animal studies or evidence of human fetal risk; use in pregnant women is contraindicated.

Main Article

Page created: October 14, 2011
Page updated: October 14, 2011
Page reviewed: October 14, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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