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Volume 12, Number 12—December 2006
Perspective

Qualitative Assessment of Risk for Monkeypox Associated with Domestic Trade in Certain Animal Species, United States

Susan M. Bernard*Comments to Author  and Steven A. Anderson*
Author affiliations: *US Food and Drug Administration, College Park, Maryland, USA

Main Article

Table 1

Disposition, as of July 11, 2003, of African rodents imported from Ghana to the United States on April 9, 2003*

Rodents Dead† Alive Lost to follow-up Total (n = 762)
Gambian giant rats 26 20 4 50
Dormice ≈350 27 ≈135 ≈510
Rope squirrels 49 4 53
Tree squirrels 24 20 3 47
Striped mice 14 50 36 100
Porcupines 2 2

*Source (1).
†Includes animals that died of monkeypox and those that have been euthanized.

*Source (1).
†Includes animals that died of monkeypox and those that have been euthanized.

Main Article

References
  1. Centers for Disease Control and Prevention. Update: multistate outbreak of monkeypox—Illinois, Indiana, Kansas, Missouri, Ohio, and Wisconsin, 2003. MMWR Morb Mortal Wkly Rep. 2003;52:6426.PubMedGoogle Scholar
  2. Centers for Disease Control and Prevention. Multistate outbreak of monkeypox–Illinois, Indiana, and Wisconsin, 2003. MMWR Morb Mortal Wkly Rep. 2003;52:53740.PubMedGoogle Scholar
  3. Reed  KD, Melski  JW, Graham  MB, Regnery  RL, Sotir  MJ, Wegner  MV, The detection of monkeypox in humans in the Western Hemisphere. N Engl J Med. 2004;350:34250. DOIPubMedGoogle Scholar
  4. Centers for Disease Control and Prevention. Monkeypox: report of cases in the United States. 2003. [cited 2006 Sept 26]. Available from http://www.cdc.gov/od/oc/media/mpv/cases.htm
  5. Di Giulio  DB, Eckburg  PB. Human monkeypox. Lancet Infect Dis. 2004;4:199. DOIPubMedGoogle Scholar
  6. Hutin  YJ, Williams  RJ, Malfait  P, Pebody  R, Loparev  VN, Ropp  SL, Outbreak of human monkeypox, Democratic Republic of Congo, 1996 to 1997. Emerg Infect Dis. 2001;7:4348.PubMedGoogle Scholar
  7. Huhn  GD, Bauer  AM, Yorita  K, Graham  MB, Sejvar  J, Likos  A, Clinical characteristics of human monkeypox, and risk factors for severe disease. Clin Infect Dis. 2005;41:174251. DOIPubMedGoogle Scholar
  8. Di Giulio  DB, Eckburg  PB. Human monkeypox: an emerging zoonosis. Lancet Infect Dis. 2004;4:1525. DOIPubMedGoogle Scholar
  9. Reynolds  MG, Cono  J, Curns  A, Holman  RC, Likos  A, Regnery  R, Human monkeypox. Lancet Infect Dis. 2004;4:6045. DOIPubMedGoogle Scholar
  10. Gerberding  JL, McClellan  MB. Joint Order of the Centers for Disease Control and Prevention and the Food and Drug Administration, Department of Health and Human Services. June 11, 2003. Available at 68 Fed Reg. 36566 (June 18, 2003).
  11. Centers for Disease Control and Prevention. Control of communicable diseases; restrictions on African rodents, prairie dogs, and certain other animals. Interim final rule. Fed Regist. 2003;68:6235369.PubMedGoogle Scholar
  12. National Research Council. Risk assessment in the federal government: managing the process. Washington: National Academy Press; 1983.
  13. Ladnyj  ID, Ziegler  P, Kima  E. A human infection caused by monkeypox virus in Basankusu Territory, Democratic Republic of the Congo. Bull World Health Organ. 1972;46:5937.PubMedGoogle Scholar
  14. Jezek  Z, Szczeniowski  M, Paluku  KM, Mutombo  M. Human monkeypox: clinical features of 282 patients. J Infect Dis. 1987;156:2938. DOIPubMedGoogle Scholar
  15. Breman  JG. Monkeypox: an emerging infection for humans? In: Scheld WM, Craig WA, Hughes JM, editors. Emerging Infections 4. Washington: ASM Press; 2000. p. 45–76.
  16. Jezek  Z, Fenner  F. Human monkeypox, in Monographs on Virology. New York: Karger; 1988.
  17. Khodakevich  L, Szczeniowski  M, Manbu-ma-Disu , Jezek  Z, Marennikova  S, Nakano  J, The role of squirrels in sustaining monkeypox virus transmission. Trop Geogr Med. 1987;39:11522.PubMedGoogle Scholar
  18. Guarner  J, Johnson  BJ, Paddock  CD, Shieh  WJ, Goldsmith  CS, Reynolds  MG, Monkeypox transmission and pathogenesis in prairie dogs. Emerg Infect Dis. 2004;10:42631.PubMedGoogle Scholar
  19. Xiao  SY, Sbrana  E, Watts  DM, Siirin  M, da Rosa  AP, Tesh  RB. Experimental infection of prairie dogs with monkeypox virus. Emerg Infect Dis. 2005;11:53945.PubMedGoogle Scholar
  20. Anderson  MG, Frenkel  LD, Homann  S, Guffey  J. A case of severe monkeypox virus disease in an American child: emerging infections and changing professional values. Pediatr Infect Dis J. 2003;22:10936. DOIPubMedGoogle Scholar
  21. Jezek  Z, Nakano  JH, Arita  I, Mutombo  M, Szczeniowski  M, Dunn  C. Serological survey for human monkeypox infections in a selected population in Zaire. J Trop Med Hyg. 1987;90:318.PubMedGoogle Scholar
  22. Jezek  Z, Marennikova  SS, Mutumbo  M, Nakano  JH, Paluku  KM, Szczeniowski  M. Human monkeypox: a study of 2,510 contacts of 214 patients. J Infect Dis. 1986;154:5515. DOIPubMedGoogle Scholar
  23. Meyer  H, Perrichot  M, Stemmler  M, Emmerich  P, Schmitz  H, Varaine  F, Outbreaks of disease suspected of being due to human monkeypox virus infection in the Democratic Republic of Congo in 2001. J Clin Microbiol. 2002;40:291921. DOIPubMedGoogle Scholar
  24. Zaucha  GM, Jahrling  PB, Geisbert  TW, Swearengen  JR, Hensley  L. The pathology of experimental aerosolized monkeypox virus infection in cynomolgus monkeys (Macaca fascicularis). Lab Invest. 2001;81:1581600.PubMedGoogle Scholar
  25. Esposito  JJ, Knight  JC. Orthopoxvirus DNA: a comparison of restriction profiles and maps. Virology. 1985;143:23051. DOIPubMedGoogle Scholar
  26. Likos  AM, Sammons  SA, Olson  VA, Frace  AM, Li  Y, Olsen-Rasmussen  M, A tale of two clades: monkeypox viruses. J Gen Virol. 2005;86:266172. DOIPubMedGoogle Scholar
  27. Arita  I, Jezek  Z, Khodakevich  L, Ruti  K. Human monkeypox: a newly emerged orthopoxvirus zoonosis in the tropical rain forests of Africa. Am J Trop Med Hyg. 1985;34:7819.PubMedGoogle Scholar
  28. Heymann  DL, Szczeniowski  M, Esteves  K. Re-emergence of monkeypox in Africa: a review of the past six years. Br Med Bull. 1998;54:693702.PubMedGoogle Scholar
  29. Antia  R, Regoes  RR, Koella  JC, Bergstrom  CT. The role of evolution in the emergence of infectious diseases. Nature. 2003;426:65861. DOIPubMedGoogle Scholar
  30. Centers for Disease Control and Prevention. Updated interim CDC guidance for use of smallpox vaccine, cidofovir, and vaccinia immunoglobulin (VIG) for prevention and treatment in the setting of an outbreak of monkeypox infections. 2003. [cited 2006 Sep 26]. Available from http://www.cdc.gov/ncidod/monkeypox/treatmentguidelines.htm
  31. Sejvar  JJ, Chowdary  Y, Schomogyi  M, Stevens  J, Patel  J, Karem  K, Human monkeypox infection: a family cluster in the midwestern United States. J Infect Dis. 2004;190:183340. DOIPubMedGoogle Scholar
  32. Edghill-Smith  Y, Golding  H, Manischewitz  J, King  LR, Scott  D, Bray  M, Smallpox vaccine–induced antibodies are necessary and sufficient for protection against monkeypox virus. Nat Med. 2005;11:7407. DOIPubMedGoogle Scholar
  33. Centers for Disease Control and Prevention. Human monkeypox—Kasai Oriental, Democratic Republic of Congo, February 1996–October 1997. MMWR Morb Mortal Wkly Rep. 1997;46:116871.PubMedGoogle Scholar
  34. Khodakevich  L, Jezek  Z, Messinger  D. Monkeypox virus: ecology and public health significance. Bull World Health Organ. 1988;66:74752.PubMedGoogle Scholar
  35. Breman  JG, Nakano  JH, Coffi  E, Godfrey  H, Gautun  JC. Human poxvirus disease after smallpox eradication. Am J Trop Med Hyg. 1977;26:27381.PubMedGoogle Scholar
  36. Hutson  CL, Lee  KN, Abel  J, Carroll  DS, Montgomery  JM, Olson  VA, Monkeypox zoonotic association: insights from laboratory evaluation of animals associated with the U.S. outbreak. Am J Trop Med Hyg. 2006. In press.
  37. Tesh  RB, Watts  DM, Sbrana  E, Siirin  M, Popov  VL, Xiao  S-Y. Experimental infection of ground squirrels (Spermophilus tridecemlineatus) with monkeypox virus. Emerg Infect Dis. 2004;10:15637.PubMedGoogle Scholar
  38. US Department of the Interior; US Geological Survey. Investigating monkeypox in the wild. Factsheet 2004–3003. July 2004. [cited 2006 Jun 13]. Available from http://www.nwhc.usgs.gov/publications/fact_sheets/pdfs/monkeypoxfinal_071504.pdf

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Page created: October 04, 2011
Page updated: October 04, 2011
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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