Volume 12, Number 3—March 2006
Dispatch
West Nile Virus–associated Flaccid Paralysis Outcome
James J. Sejvar*
, Amy V. Bode†, Anthony A. Marfin†, Grant L. Campbell†, John Pape‡, Brad J. Biggerstaff†, and Lyle R. Petersen†
, Amy V. Bode†, Anthony A. Marfin†, Grant L. Campbell†, John Pape‡, Brad J. Biggerstaff†, and Lyle R. Petersen†
Table
Signs and symptoms in 32 patients with West Nile virus (WNV)–associated paralysis
| Sign/symptom | Acute infection, N = 32, no. (%) | 4-mo followup, N = 27, no. (%) | 1-y followup, N = 22, no. (%) |
|---|---|---|---|
| Fever (temperature >38°C) | 29 (91) | 0 | 0 |
| Nausea (with or without vomiting) | 26 (81) | 0 | 0 |
| Headache | 28 (88) | 5 (19) | 3 (11) |
| Altered mental status | 16 (50) | 0 | 1 (5) |
| Meningismus | 10 (31) | 0 | 0 |
| Rash | 4 (13) | 0 | 0 |
| WNV-associated neurologic features* | |||
| Tremor | 21 (66) | 8 (25) | 9* (41) |
| Myoclonus | 15 (47) | 2 (6) | 3* (14) |
| Parkinsonism | 8 (25) | 2 (6) | 5* (23) |
| Cerebellar ataxia | 3 (9) | 2 (6) | 1 (5)5 |
| Limb atrophy | 0 | 17 (53) | 10 (45) |
*An apparent increase in the number of persons with tremor, myoclonus, and parkinsonism between 4 mo and 1 y is reflective of detection of these movement disorders in persons who were initially flaccid/immobile, nonambulatory, or too functionally impaired to assess.
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