TY - JOUR AU - Sanchez, Lizet AU - Vanlerberghe, Veerle AU - Alfonso, Lázara AU - Marquetti, María del Carmen AU - Guzman, María Guadalupe AU - Bisset, Juan AU - van der Stuyft, Patrick T1 - Aedes aegypti Larval Indices and Risk for Dengue Epidemics T2 - Emerging Infectious Disease journal PY - 2006 VL - 12 IS - 5 SP - 800 SN - 1080-6059 AB - We assessed in a case-control study the test-validity of Aedes larval indices for the 2000 Havana outbreak. "Cases" were blocks where a dengue fever patient lived during the outbreak. "Controls" were randomly sampled blocks. Before, during, and after the epidemic, we calculated Breteau index (BI) and house index at the area, neighborhood, and block level. We constructed receiver operating characteristic (ROC) curves to determine their performance as predictors of dengue transmission. We observed a pronounced effect of the level of measurement. The BImax (maximum block BI in a radius of 100 m) at 2-month intervals had an area under the ROC curve of 71%. At a cutoff of 4.0, it significantly (odds ratio 6.00, p<0.05) predicted transmission with 78% sensitivity and 63% specificity. Analysis of BI at the local level, with human-defined boundaries, could be introduced in control programs to identify neighborhoods at high risk for dengue transmission. KW - Aedes aegypti control KW - larval indices KW - dengue KW - transmission risk KW - surveillance KW - Cuba KW - research DO - 10.3201/eid1205.050866 UR - https://wwwnc.cdc.gov/eid/article/12/5/05-0866_article ER - End of Reference