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Volume 12, Number 9—September 2006
Dispatch

Mycobacterium bovis Infection, Lyon, France

Sophie Mignard*†Comments to Author , Catherine Pichat*, and Gerard Carret*†
Author affiliations: *Centre Hospitalier Lyon Sud, Lyon, France; †Centre National de la Recherche Scientifique, Lyon, France

Main Article

Table 2

Spoligotyping and MIRU typing results

Patient Strain Spoligotype IP* International spoligotype† MIRU type‡ Spoligotypes
SO M. bovis 481 SB0121 23232 42533 22 ■■□■■■■■□■■■■■■□■■■■□■■■■■■■■■■■■■■■■■□□□□□
GD M. bovis BCG 482 SB0120 22232 42533 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
BS M. bovis 482 SB0120 23232 42512 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
MB M. bovis Not present Not present 23232 42533 22 ■■□□□□□■□■■■■■■□■■■■■■■□□□■□□□□□□□□□□■□□□□□
KA M. bovis 482 SB0120 22232 52523 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
GA M. ovis 481 SB0121 23232 42333 22 ■■□■■■■■□■■■■■■□■■■■□■■■■■■■■■■■■■■■■■□□□□□
PC M. bovis 482 SB0120 23232 42423 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
TG M. bovis 482 SB0120 23232 42523 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
FJ M. bovis 482 SB0120 22232 42523 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
OM M. bovis Not present SB0914 23242 42533 22 ■■□■■■■■□□□■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
GA M. bovis 482 SB0120 23202 42523 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
BL M. bovis BCG 482 SB0120 21232 42533 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□
RM M. bovis 482 SB0120 22231 43533 22 ■■□■■■■■□■■■■■■□■■■■■■■■■■■■■■■■■■■■■■□□□□□

*IP, Pasteur Institute Spoligotype Database; available from http://www.pasteur-guadeloupe.fr/tb/spoldb3/spoldb3.pdf
†International Spoligotype Database; available from http://www.Mbovis.org (10).
‡Mycobacterial interspersed repeat units (MIRU) type described by Supply et al. (11; available at http://www.ibl.fr/mirus/mirus.htm).

Main Article

References
  1. Haddad  N, Ostyn  A, Karoui  C, Masselot  M, Thorel  MF, Hughes  SL, Spoligotype diversity of Mycobacterium bovis strains isolated in France from 1979 to 2000. J Clin Microbiol. 2001;39:362332. DOIPubMedGoogle Scholar
  2. Boulahbal  F, Robert  J, Trystram  D, de Benoist  AC, Vincent  V, Jarlier  V, La tuberculose humaine à Mycobacterium bovis en France durant l'année 1995. Bulletin Epidemiologique Hebdomadaire. 1998;48.
  3. Frothingham  R, Meeker-O'Connell  WA. Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. Microbiology. 1998;144:118996. DOIPubMedGoogle Scholar
  4. Allix  C, Supply  P, Fauville-Dufaux  M. Utility of fast mycobacterial interspersed repetitive unit-variable number tandem repeat genotyping in clinical mycobacteriological analysis. Clin Infect Dis. 2004;39:7839. DOIPubMedGoogle Scholar
  5. Gibson  AL, Hewinson  G, Goodchild  T, Watt  B, Story  A, Inwald  J, Molecular epidemiology of disease due to Mycobacterium bovis in humans in the United Kingdom. J Clin Microbiol. 2004;42:4314. DOIPubMedGoogle Scholar
  6. Skuce  RA, Neill  SD. Molecular epidemiology of Mycobacterium bovis: exploiting molecular data. Tuberculosis (Edinb). 2001;81:16975. DOIPubMedGoogle Scholar
  7. Scorpio  A, Collins  D, Whipple  D, Cave  D, Bates  J, Zhang  Y. Rapid differentiation of bovine and human tubercle bacilli based on a characteristic mutation in the bovine pyrazinamidase gene. J Clin Microbiol. 1997;35:10610.PubMedGoogle Scholar
  8. Talbot  EA, Williams  DL, Frothingham  R. PCR identification of Mycobacterium bovis BCG. J Clin Microbiol. 1997;35:5669.PubMedGoogle Scholar
  9. Kamerbeek  J, Schouls  L, Kolk  A, Van Agterveld  M, Van Soolingen  D, Kuijper  S, Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology. J Clin Microbiol. 1997;35:90714.PubMedGoogle Scholar
  10. Mycobacterium bovis international database [cited 2005 November 20]. Available from http://www.Mbovis.org
  11. Supply  P, Lesjean  S, Savine  E, Kremer  K, Van Soolingen  D, Locht  C. Automated high-throughput genotyping for study of global epidemiology of Mycobacterium tuberculosis based on myobacterial interspersed repetitive units. J Clin Microbiol. 2001;39:356371. DOIPubMedGoogle Scholar
  12. MIRU-VNTR allele tables [cited 2005 Nov 20]. Available from http://www.iblt.fr/mirus/mirus.html
  13. Sales  MP, Taylor  GM, Hughes  S, Yates  M, Hewinson  G, Young  DB, Genetic diversity among Mycobacterium bovis isolates: a preliminary study of strains from animal and human sources. J Clin Microbiol. 2001;39:455862. DOIPubMedGoogle Scholar
  14. Supply  P, Mazars  E, Lesjean  S, Vincent  V, Gicquel  B, Locht  C. Variable human minisatellite-like regions in the Mycobacterium tuberculosis genome. Mol Microbiol. 2000;36:76271. DOIPubMedGoogle Scholar
  15. Smith  RM, Drobniewski  F, Gibson  A, Montague  JD, Logan  MN, Hunt  D, Mycobacterium bovis infection, United Kingdom. Emerg Infect Dis. 2004;10:53941.PubMedGoogle Scholar
  16. Centers for Disease Control and Prevention. Human tuberculosis caused by Mycobacterium bovis—New York City, 2001–2004. MMWR Morb Mortal Wkly Rep. 2005;54:6058.PubMedGoogle Scholar

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