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Volume 13, Number 12—December 2007
Research

Susceptibility of Canada Geese (Branta canadensis) to Highly Pathogenic Avian Influenza Virus (H5N1)

John Pasick*Comments to Author , Yohannes Berhane*, Carissa Embury-Hyatt*, John Copps*, Helen Kehler*, Katherine Handel*, Shawn Babiuk*, Kathleen Hooper-McGrevy*, Yan Li†, Quynh Mai Le‡, and Song Lien Phuong§
Author affiliations: *Canadian Food Inspection Agency, Winnipeg, Manitoba, Canada; †Public Health Agency of Canada, Winnipeg, Manitoba, Canada; ‡National Institute of Hygiene and Epidemiology, Hanoi, Vietnam; §National Center for Veterinary Diagnosis, Hanoi, Vietnam;

Main Article

Table 1

NP and H5 antibody levels in juvenile and adult Canada geese*

Animal ID 0 dpi cELISA 
(NP % inhibition) 0 dpi H5 HI assay† 14 dpi (H5N2) cELISA (NP % inhibition) 21 dpi (H5N2)
H5 HI assay† 20–21 dpi (H5N1)
cELISA (NP) 20–21 dpi (H5N1)
H5 HI assay†
Juveniles
852S/27R Neg (20) <8 Pos (66) 16 Euthanized or died‡
853S/28R Neg (13) <8 Pos (64) 64 Pos (46% inhibition) 8
856S/31R Neg (21) <8 Pos (57) 256 Euthanized
858S/33R Neg (22) <8 Pos (55) 128 Pos (48% inhibition) 64
859S/34R Neg (19) <8 Pos (49) 256 Euthanized
851S/26R Neg (24) <8 Euthanized
854S/29R Neg (23) <8 Euthanized
855S/30R Neg (22) <8 Euthanized
860S/35R Neg (24) <8 Euthanized
861S/36R Neg (20) <8
857S/32Y Neg (18) <8
Adults
842S/42Y Pos (93) <8 Pos (99) 512 Euthanized
844S/44Y Neg (23) <8 Pos (99) 64 Pos (46% inhibition) <8
845S/45Y Pos (58) <8 Pos (96) 8 Euthanized
846S/46Y Pos (76) <8 Pos (96) <8 Pos (63% inhibition) <8
847S/47Y Pos (74) <8 Pos (99) ND Euthanized
840S/40Y Pos (45) <8 Pos (99% inhibition) >4,096
841S/41Y Neg (22) <8 Euthanized
843S/43Y Pos (78) <8 Euthanized
848S/48Y Pos (39) <8 Pos (98% inhibition) 64
849S/49Y Pos (93) <8 Pos (98% inhibition) 32
850S/50Y Pos (85) <8

*NP, nucleoprotein; cELISA, competitive ELISA; dpi, days postinfection; Neg, negative (<30% inhibition); Pos, positive (≥30% inhibition); HI, hemagglutinin inhibition; ND, not determined.
4 hemagglutinin units of A/duck/British Columbia/26–6/2005 (H5N2) used in assay.
‡Euthanized or died before day 20–21 postinoculation with virus (H5N1).

Main Article

Page created: July 06, 2010
Page updated: July 06, 2010
Page reviewed: July 06, 2010
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