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Volume 13, Number 12—December 2007
Dispatch

Clinical and Epidemiologic Characterization of WU Polyomavirus Infection, St. Louis, Missouri

Binh-Minh Le*, Lee M. Demertzis*, Guang Wu*, Robert J. Tibbets*, Richard S. Buller*, Max Q. Arens*, Anne M. Gaynor*, Gregory A. Storch*, and David Wang*Comments to Author 
Author affiliations: *Washington University School of Medicine, St. Louis, Missouri, USA;

Main Article

Table

Clinical parameters in episodes of WU polyomavirus infection

Symptoms and physical examination findings (n = 65) %
Symptoms
Cough 57
Upper respiratory tract symptoms 55
Rhonchi/crackles/coarse breath sounds 46
Shortness of breath or increased work of breathing 42
Wheezing 40
Rhinorrhea 38
Retractions 37
Decreased oral intake 34
Vomiting 32
Diarrhea 18
Stridor 6
Rash 6
Apnea 5
Signs
Tachypnea* (n = 57) 79
Hypoxia† (n = 55) 47
Fever‡ (n = 63) 41
Bandemia (n = 42) 40
Leukocytosis§ (n = 42) 31
Leukopenia¶ (n = 42) 10
Radiographic or computed tomographic findings (n = 50)
Infiltrate or consolidation 72
Hyperinflation 14
Peribronchial cuffing 12
Effusions 6
Treatment
Antimicrobial agents (n = 65) 58
Bronchodilators (n = 65) 38
Steroids (n = 65) 37
Oxygen (n = 65) 25
Intubation (n = 63) 11
Intensive care (n = 63) 19
Risk factors
Daycare 32
Sick contacts 25
Medical history
Asthma (n = 60) 37

*Defined per National Institutes of Health clinical center guidelines.
†SaO2 <95% or PaO2 >80%.
‡Temperature >38°C.
§Leukocyte count >15,000/mm3.
¶Leukocyte count <4,000/mm3.

Main Article

Page created: July 06, 2010
Page updated: July 06, 2010
Page reviewed: July 06, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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