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Volume 13, Number 2—February 2007

Pneumocystis Pneumonia in HIV-positive Adults, Malawi1

Joep J.G. van Oosterhout*, Miriam K. Laufer†, M. Arantza Perez*, Stephen M. Graham*, Nelson Chimbiya*, Phillip C. Thesing*, Miriam J. Álvarez-Martinez‡, Paul E. Wilson‡, Maganizo Chagomerana*, Eduard E. Zijlstra*, Terrie E. Taylor*§, Christopher V. Plowe†Comments to Author , and Steven R Meshnick‡
Author affiliations: *University of Malawi, Blantyre, Malawi;; †University of Maryland School of Medicine, Baltimore, Maryland, USA; ‡University of North Carolina, Chapel Hill, North Carolina, USA; §Michigan State University, East Lansing, Michigan, USA;

Main Article

Table 2

Outcomes in 95 episodes of suspected Pneumocystis pneumonia (PcP), Malawi, 2002–2004*

Final diagnosis†Clinical diagnosis‡No. episodesIFPCRFollow-up data
Confirmed PcPPcP2PosPos
Confirmed PcPPcP1NegPos
Confirmed PcPPcP1Death after 2 wk of PcP treatment (IS not done due to respiratory distress)
Confirmed PcPBronchiectasies1NegPosDeath 1 wk after IS
Confirmed PcPTuberculosis1NegPosImprovement but short follow-up (2 wk)
Pneumocystis colonization/pulmonary KSPulmonary KSNegPosDeath 23 wk after first IS
Pneumocystis colonization/tuberculosisTuberculosis3NegPosRecovery
Pneumocystis colonization/bacterial pneumoniaBacterial pneumonia2NegPosRecovery
Pneumocystis colonization/unspecified respiratory illnessUnspecified respiratory illness2NegPosRecovery
Pneumocystis colonization/other diagnosisOther diagnosis¶1NegPosRecovery
Unspecified respiratory illnessPcP3NegNeg
Bacterial pneumoniaBacterial pneumonia10NegNeg
Unspecified respiratory illnessUnspecified respiratory illness20NegNeg
Unspecified respiratory illnessUnspecified respiratory illness1NegNARecovery (18 wk follow-up)
Other diagnoses¶Other diagnoses¶24NegNeg
Other diagnosis¶Other diagnosis¶1NegNARecovery (>1 y follow-up)

*IF, immunofluorescence stain; pos, positive; neg, negative; IS, induced sputum procedure; KS, Kaposi sarcoma.
†Diagnosis based on clinical evidence, IF, and PCR from an IS sample, and follow-up after episode.
Diagnosis based on clinical evidence and IF from an IS sample.
§Three episodes occurring in 1 person.
¶Among other diagnoses were sepsis, bronchitis, emphysema, pulmonary KS, and bronchiectasis.

Main Article

1Data from this study were presented in part at 9th College of Medicine Research Dissemination Conference, Blantyre, Malawi, 12 Nov 2005 (abstract DCON/05/44), and XV International AIDS Conference, Bangkok, Thailand, 11–16 Jul 2004 (abstract MoPeB3198).

Page created: June 29, 2010
Page updated: June 29, 2010
Page reviewed: June 29, 2010
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