TY - JOUR AU - Yamane, Kunikazu AU - Wachino, Jun-ichi AU - Suzuki, Satowa AU - Shibata, Naohiro AU - Kato, Haru AU - Shibayama, Keigo AU - Kimura, Kouji AU - Kai, Kumiko AU - Ishikawa, Satoshi AU - Ozawa, Yoshiyuki AU - Konda, Toshifumi AU - Arakawa, Yoshichika T1 - 16S rRNA Methylase–producing, Gram-Negative Pathogens, Japan T2 - Emerging Infectious Disease journal PY - 2007 VL - 13 IS - 4 SP - 642 SN - 1080-6059 AB - To investigate the exact isolation frequency of 16S rRNA methylase–producing, gram-negative pathogenic bacteria, we tested 87,626 clinical isolates from 169 hospitals. Twenty-six strains from 16 hospitals harbored 16S rRNA methylase genes, which suggests sparse but diffuse spread of pan-aminoglycoside–resistant microbes in Japan. KW - Aminoglycoside resistance KW - 16S rRNA methylase KW - gram-negative bacteria KW - dispatch KW - Japan DO - 10.3201/eid1304.060501 UR - https://wwwnc.cdc.gov/eid/article/13/4/06-0501_article ER - End of Reference