Volume 14, Number 10—October 2008
Perspective
Rise and Persistence of Global M1T1 Clone of Streptococcus pyogenes
Table
Genomic differences between M1T1 and M1 SF370*
Difference | M1T1 | SF370 |
---|---|---|
Prophages or prophage remnants | SPhinX (speA2), MemPhiS (mf3/mf4), PhiRamid (sda1) | 370.1 (mf2, speC), 370.2 (speH, speI), 370.3 (mf3), 370.4 (phage remnant) |
Superantigen genes | speA2, speG, speJ, smeZ1, | speC, speG, speH, speI, speJ, smeZ1 |
Streptodornases | mf/spd, mf3/spd OR mf4/spd4, sda1 | mf/spd, mf2, mf3/spd3 |
Other | Insertion sequence (IS1548), SNP in the SLO/NADGH region |
*SNP, single nucleotide polymorphism; SLO, streptolysin O; NADGH, nicotinamide glycohydrolase. Toxin gene names in boldface designate genes that are unique to either strain.