Volume 14, Number 2—February 2008
Research
Genetic Determinants of Virulence in Pathogenic Lineage 2 West Nile Virus Strains
Elizabeth M. Botha*, Wanda Markotter*, Mariaan Wolfaardt*, Janusz T. Paweska†, Robert Swanepoel†, Gustavio Palacios‡, Louis H. Nel*, and Marietjie Venter*
Table 3
Percentage amino acid and nucleotide differences when comparing individual proteins of selected West Nile virus strains*
| Strain | SA381/00 | H442 | SPU116/89 | SA93/01 |
|---|---|---|---|---|
| Capsid |
||||
| SA381/00 | ||||
| H442 | 0 | |||
| SPU116/89 | 0 | 0 | ||
| SA93/01 |
0 |
0 |
0 |
|
| Envelope |
||||
| SA381/00 | ||||
| H442 | 0.8 | |||
| SPU116/89 | 0.2 | 0.6 | ||
| SA93/01 |
0.2 |
0.6 |
0 |
|
| NS2A/B |
||||
| SA381/00 | ||||
| H442 | 0.6 | |||
| SPU116/89 | 0.3 | 0.8 | ||
| SA93/01 |
0.3 |
0.8 |
0 |
|
| NS4A/B |
||||
| SA381/00 | ||||
| H442 | 0.2 | |||
| SPU116/89 | 0.2 | 0.5 | ||
| SA93/01 |
0 |
0.2 |
0.2 |
|
| prM |
||||
| SA381/00 | ||||
| H442 | 0.6 | |||
| SPU116/89 | 0.6 | 0 | ||
| SA93/01 |
0.6 |
0 |
0 |
|
| NS1 |
||||
| SA381/00 | ||||
| H442 | 0.9 | |||
| SPU116/89 | 0.9 | 0 | ||
| SA93/01 |
1.1 |
0.3 |
0.3 |
|
| NS3 |
||||
| SA381/00 | ||||
| H442 | 0.8 | |||
| SPU116/89 | 0.6 | 0.5 | ||
| SA93/01 |
0.6 |
0.5 |
0 |
|
| NS5 |
||||
| SA381/00 | ||||
| H442 | 0.8 | |||
| SPU116/89 | 2.1 | 1.5 | ||
| SA93/01 | 1.9 | 1.3 | 2.0 | |
*prM, premembrane; NS, nonstructural.
Page created: July 07, 2010
Page updated: July 07, 2010
Page reviewed: July 07, 2010
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