Volume 14, Number 3—March 2008
Leptospirosis-associated Severe Pulmonary Hemorrhagic Syndrome, Salvador, Brazil
|Characteristics*||No. responses||No. (%) or mean ± SD|
|Onset of massive hemoptysis|
|During hospital admission||47||7 (15)|
|After hospitalization and before endotracheal intubation||47||21 (45)|
|During or after endotracheal intubation
|Chest radiographic examination|
|Bilateral alveolar infiltrates||24||21 (88)|
|Bilateral interstitial infiltrates
|PaO2/FiO2, mm Hg||33||200 ± 155|
|Acute lung injury†||33||25 (76)|
|Acute respiratory distress syndrome‡||33||21 (64)|
*Findings at initial evaluation. SD, standard deviation.
†Defined as a ratio between arterial partial pressure of O2 and inspired O2 fraction (PaO2/FiO2) <300 mm Hg and the presence of bilateral alveolar or interstitial infiltrates on chest radiograph or bilateral crepitus on physical examination, without clinical evidence of increased left atrial pressure.
‡Defined as PaO2/FiO2 <200 mm Hg in addition to criteria for acute lung injury.