Volume 14, Number 9—September 2008
Dispatch
Crack Cocaine and Infectious Tuberculosis
Table 2
Multivariate analysis of risk factors for smear-positive disease on diagnosis among drug-using and non–drug-using patients with pulmonary TB in London, UK, 2003–2004*
Variable | OR | 95% CI | p value |
---|---|---|---|
Not a hard-drug user | Baseline | ||
Hard-drug user (not known to use crack cocaine) | 1.87 | 1.19–2.95 | 0.007 |
Crack cocaine user |
6.59 |
1.78–24.31 |
0.005 |
Age, y | |||
0–14 | 0.10 | 0.08–0.56 | 0.002 |
15–29 | 1.10 | 0.81–1.48 | 0.55 |
30–59 | Baseline | ||
>60 |
0.69 |
0.45–1.14 |
0.14 |
Ethnicity | |||
South Asian | Baseline | ||
Black African | 1.75 | 0.96–1.95 | 0.08 |
White | 1.51 | 0.99–2.31 | 0.053 |
Black Caribbean | 2.70 | 1.34–5.43 | 0.005 |
Other ethnicity |
1.61 |
0.91–2.85 |
0.101 |
No drug resistance | Baseline | ||
INH (not outbreak strain) | 1.23 | 0.72–2.11 | 0.441 |
INH (outbreak strain) | 0.96 | 0.37–2.50 | 0.929 |
MDR | 2.90 | 1.44–5.78 | 0.003 |
Sought treatment at ED | 3.33 | 2.20–4.82 | <0.001 |
*OR, odds ratio; CI, confidence interval; INH, isoniazid resistant; MDR, multidrug-resistant; ED, emergency department.