Volume 14, Number 9—September 2008
Excretion of Transmissible Spongiform Encephalopathy Infectivity in Urine
|Hamster||Volume assayed, mL||Fold dilution||Volume inoculated, mL||Total no. hamsters||No. infected hamsters||Titer, ID/mL*||SD†|
*ID, infectious dose. Titer = –ln(P(0)) × (1/v), where P(0) = (noninfected animals)/(total animals inoculated) and v = inoculation volume, 0.05 mL.
†SD = square root (titer/V), where V = 4.87 mL, the total volume of the undiluted urine inoculated (1).
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