Evaluation of Commercially Available Anti–Dengue Virus Immunoglobulin M Tests
Elizabeth A. Hunsperger, Sutee Yoksan, Philippe Buchy, Vinh Chau Nguyen, Shamala D. Sekaran, Delia A. Enria, Jose L. Pelegrino, Susana Vázquez, Harvey Artsob, Michael Drebot, Duane J. Gubler, Scott B. Halstead, María G. Guzmán, Harold S. Margolis, Carl-Michael Nathanson, Nidia R. Rizzo Lic, Kovi E. Bessoff, Srisakul Kliks, and Rosanna W. Peeling
Author affiliations: Centers for Disease Control and Prevention, San Juan, Puerto Rico, USA (E.A. Hunsperger, K.E. Bessoff); Mahidol University, Bangkok, Thailand (S. Yoksan); Institut Pasteur, Phnom Penh, Cambodia (P. Buchy); Cho Quan Hospital, Ho Chi Minh City, Vietnam (V.C. Nguyen); University of Malaya, Kuala Lumpur, Malaysia (S.D. Sekaran); Instituto Nacional Enfermedades Virales Humanas Dr. Julio I. Maiztegui, Buenos Aires, Argentina (D.A. Enria); Instituto Medicina Tropical Pedro Kouri, Havana, Cuba (S. Vázquez, M.G. Guzmán, J.L. Pelegrino); Public Health Agency of Canada, Winnipeg, Manitoba, Canada (H. Artsob, M. Drebot); University of Hawaii, Honolulu, Hawaii, USA (D.J. Gubler); Pediatric Dengue Vaccine Initiative, Seoul, South Korea (S.B. Halstead, H.S. Margolis, S. Kliks); World Health Organization, Geneva, Switzerland (C.-M. Nathanson, N.R. Rizzo, R.W. Peeling)
Figure 2. Percentages of false-positive results for 4 rapid diagnostic tests (RDTs) (left panel) and 5 microplate ELISAs (right panel). Numbers of samples tested are shown in parentheses. Neg, negative; DEN, dengue; IgG, immunoglobulin G; WNV West Nile virus; YF, yellow fever; StLEnc, St. Louis encephalitis; JE, Japanese encephalitis; Lyme, Lyme disease; HTN, New World hantavirus; RF, rheumatoid factor; SLE, systemic lupus erythematosus.
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