Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 15, Number 4—April 2009
Research

Novel Type of Streptococcus pneumoniae Causing Multidrug-Resistant Acute Otitis Media in Children

Qingfu Xu, Michael E. Pichichero, Janet R. Casey, and Mingtao ZengComments to Author 
Author affiliations: University of Rochester School of Medicine and Dentistry, Rochester, New York, USA (Q. Xu, M.E. Pichichero, M. Zeng); Legacy Pediatrics, Rochester (M.E. Pichichero, J.R. Casey)

Main Article

Table 1

Genotypic characteristics of Streptococcus pneumoniae serotype 19A strains with multiple antimicrobial drug resistance*

Strain Sequence type MIC, µg/mL
Allele no. of housekeeping genes†
Pen Cef Ery S.Tri aroE gdh gki recP spi xpt ddl
P270CR 320 2.0 1.0 >256 >32 4 16 19 15 6 20 1
060110 1451 4.0 1.0 >256 4.0 10 16 19 15 6 20 1
P270CL 320 2.0 1.0 >256 >32 4 16 19 15 6 20 1
Legacy strain 2722‡ 8.0 6.0 8.0 >32 7 11 10 15 6 8 1
P239CR 320 2.0 2.0 >256 8.0 4 16 19 5 6 20 1
0601034 320 2.0 1.0 >256 16.0 4 16 19 15 6 20 1
0601004V1NW 320 2.0 1.5 >256 6.0 4 16 19 15 6 20 1
0601004V1LMEF 320 3.0 1.5 >256 4.0 4 16 19 15 6 20 1

*Pen, benzylpenicillin; Cef, ceftriaxone; Ery, erythromycin; S.Tri, sulfamethoxazole-trimethoprim.
aroE (shikimate dehydrogenase), gdh (glucose-6-phosphate dehydrogenase), gki (glucose kinase), recP (transketolase), spi (signal peptidase I), xpt (xanthine phosphoribosyltransferase), and ddl (D-alanine-D-alanine ligase).
‡New assigned sequence type.

Main Article

Page created: December 10, 2010
Page updated: December 10, 2010
Page reviewed: December 10, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external