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Volume 15, Number 5—May 2009

Probable Congenital Babesiosis in Infant, New Jersey, USA

Sonia Sethi, David Alcid, Hemant Kesarwala, and Robert W. TolanComments to Author 
Author affiliations: The Children’s Hospital at Monmouth Medical Center, Long Branch, New Jersey, USA (S. Sethi); Saint Peter’s University Hospital, New Brunswick, New Jersey, USA (D. Alcid, H. Kesarwala, R.W. Tolan, Jr.); Robert Wood Johnson Medical School, New Brunswick (D. Alcid); Drexel University College of Medicine, Philadelphia, Pennsylvania, USA (H. Kesarwala, R.W. Tolan, Jr.)

Main Article

Table 2

Selected clinical data from the first 2 reported cases of congenital babesiosis (3,4) and the probable case described in this article*

Clinical data Reference case 1 Reference case 2 Present case
Infant’s age at time of illness 30 d 5 wk 26 d
Time of maternal tick bite before delivery
1 wk
7 wk
4 wk
Serologic test results for Babesia spp.
Mother Pos Pos Pos
Clinical findings Fever, irritability, pallor, hepatosplenomegaly Lethargy, poor feeding, pallor Fever, poor feeding, irritability, pallor, scleral icterus, hepatosplenomegaly
Parasitemia, % 5 4.4 15
Treatment (duration) Ampicillin and gentamicin (3 d); clindamycin and quinine sulfate (10 d) Clindamycin and quinine sulfate (12 d); azithromycin (10 d) Ceftriaxone (8 d); atovaquone and azithromycin (10 d)

*All infants’ history of tick exposure was negative, and all recovered.

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