Volume 15, Number 6—June 2009
Oseltamivir- and Amantadine-Resistant Influenza Viruses A (H1N1)
|Characteristics||No. isolates||HA clade||NA clade||M2 clade||Mutation|
|Oseltamivir resistant (n = 84)|
|Amantadine susceptible||81||2B†||2B||2B||H274Y in NA|
|Amantadine resistant||1||2C†||2B||2C||H274Y in NA, S31N in M2|
||H274Y in NA, S31N in M2
|Oseltamivir susceptible (n = 37)|
|Amantadine resistant||14||2C||2C||2C||S31N in M2|
|3||2B||2B||2C||S31N in M2|
*HA, hemagglutinin; NA, neuraminidase; M2, matrix.
†Clade 2B or clade 2C indicates the gene specified has a nucleotide homology >99% to that of A/Brisbane/59/2007 or A/Hong Kong/2652/2006 virus, respectively.
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