Susceptibilities of Nonhuman Primates to Chronic Wasting Disease
Brent Race
1
, Kimberly D. Meade-White
1, Michael W. Miller, Kent D. Barbian, Richard Rubenstein, Giuseppe LaFauci, Larisa Cervenakova, Cynthia Favara, Donald Gardner, Dan Long, Michael Parnell, James Striebel, Suzette A. Priola, Anne Ward, Elizabeth S. Williams
2, Richard Race
3, and Bruce Chesebro
3
Author affiliations: Rocky Mountain Laboratories, Hamilton, Montana, USA (B. Race, K.D. Meade-White, K.D. Barbian, C. Favara, D. Gardner, D. Long, M. Parnell, J. Striebel, S.A. Priola, A. Ward, R. Race, B. Chesebro); Colorado Division of Wildlife, Fort Collins, Colorado, USA (M.W. Miller); State University of New York Downstate Medical Center, Brooklyn, New York, USA (R. Rubenstein); New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA (G. LaFauci); American Red Cross, Rockville, Maryland, USA (L. Cervenakova); University of Wyoming, Laramie, Wyoming, USA (E.S. Williams)
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Table 3
Cynomolgus macaques infected with CWD agent*
No. monkeys |
CWD inoculum |
Route of inoculation |
Titer inoculated† |
Current mpi |
1 (no. 609)‡ |
MD-1 |
Intracerebral |
2.5 × 106 |
NA |
1 |
MD-1 |
Intracerebral |
2.5 × 106 |
70 |
3 |
MD-1 |
Oral |
2.0 × 109 |
70 |
2 |
Elk-1 |
Intracerebral |
3.2 × 105 |
70 |
3 |
Elk-1 |
Oral |
2.5 × 108 |
70 |
2 |
WTD-1 |
Intracerebral |
1.0 × 106 |
70 |
3 |
WTD-1 |
Oral |
1.2 × 109 |
70 |
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Page created: December 07, 2010
Page updated: December 07, 2010
Page reviewed: December 07, 2010
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