TY - JOUR AU - Varma, Jay K. AU - McCarthy, Kimberly D. AU - Tasaneeyapan, Theerawit AU - Monkongdee, Patama AU - Kimerling, Michael E. AU - Buntheoun, Eng AU - Sculier, Delphine AU - Keo, Chantary AU - Phanuphak, Praphan AU - Teeratakulpisarn, Nipat AU - Udomsantisuk, Nibondh AU - Dung, Nguyen H. AU - Lan, Nguyen T.N. AU - Yen, Nguyen T.B. AU - Cain, Kevin P. T1 - Bloodstream Infections among HIV-Infected Outpatients, Southeast Asia T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 10 SP - 1569 SN - 1080-6059 AB - Bloodstream infections (BSIs) are a major cause of illness in HIV-infected persons. To evaluate prevalence of and risk factors for BSIs in 2,009 HIV-infected outpatients in Cambodia, Thailand, and Vietnam, we performed a single Myco/F Lytic blood culture. Fifty-eight (2.9%) had a clinically significant BSI (i.e., a blood culture positive for an organism known to be a pathogen). Mycobacterium tuberculosis accounted for 31 (54%) of all BSIs, followed by fungi (13 [22%]) and bacteria (9 [16%]). Of patients for whom data were recorded about antiretroviral therapy, 0 of 119 who had received antiretroviral therapy for >14 days had a BSI, compared with 3% of 1,801 patients who had not. In multivariate analysis, factors consistently associated with BSI were fever, low CD4+ T-lymphocyte count, abnormalities on chest radiograph, and signs or symptoms of abdominal illness. For HIV-infected outpatients with these risk factors, clinicians should place their highest priority on diagnosing tuberculosis. KW - Tuberculosis and other mycobacteria KW - HIV/AIDS and other retroviruses KW - diagnosis KW - bacteria KW - Salmonella KW - cryptoccoci KW - penicilliosis KW - fungi KW - research KW - Cambodia KW - Thailand KW - Vietnam DO - 10.3201/eid1610.091686 UR - https://wwwnc.cdc.gov/eid/article/16/10/09-1686_article ER - End of Reference