TY - JOUR AU - Reißmann, Silvana AU - Friedrichs, Claudia AU - Rajkumari, Reena AU - Itzek, Andreas AU - Fulde, Marcus AU - Rodloff, Arne C. AU - Brahmadathan, Kootallur N. AU - Chhatwal, Gursharan S. AU - Nitsche-Schmitz, D. Patric T1 - Contribution of Streptococcus anginosus to Infections Caused by Groups C and G Streptococci, Southern India T2 - Emerging Infectious Disease journal PY - 2010 VL - 16 IS - 4 SP - 656 SN - 1080-6059 AB - Vellore, a region in southern India, has a high incidence of severe human infections with β-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006–2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research. KW - Streptococcus anginosus KW - streptococci KW - groups C and G streptococci KW - suppurative infections KW - pharyngitis KW - bacteria KW - abscesses KW - research KW - India DO - 10.3201/eid1604.090448 UR - https://wwwnc.cdc.gov/eid/article/16/4/09-0448_article ER - End of Reference