Transmission of Hemagglutinin D222G Mutant Strain of Pandemic (H1N1) 2009 Virus
, Marzia Facchini, Domenico Spagnolo, Maria A. De Marco, Laura Calzoletti, Alessandro Zanetti, Roberto Fumagalli, Maria L. Tanzi, Antonio Cassone, Istituto Superiore di Sanità, Isabella Donatelli, and the Surveillance Group for Pandemic A (H1N1) 2009 Influenza Virus in Italy1
Author affiliations: National Institute of Health, Rome, Italy (S. Puzelli, M. Facchini, D. Spagnolo, M.A. De Marco, L. Calzoletti, A. Cassone, G. Rezza, I. Donatelli); Università degli Studi di Milano, Milan, Italy (A. Zanetti); Università degli Studi di Milano-Bicocca, Milan (R. Fumagalli); Università degli Studi di Parma, Parma, Italy (M.L. Tanzi)
Figure. Phylogenetic relationships of hemagglutinin (HA) 1 sequences of pandemic (H1N1) 2009 viruses in Italy obtained from the National Influenza Centre (NIC)–Istituto Superiore di Sanità (ISS) and the National Center for Biotechnology Information. The NIC-ISS sequences are in italics. Isolates from the index case-patient and his father are indicated in boldface. Amino acid mutations of interest in this study are reported on the nodes. All the NIC sequences obtained in the present study were deposited in the GenBank database under the following accession numbers: (hemagglutinin sequences) GU451262–GU451280; GU576500–GU576502; GU576504; GU576506; GU576508; GU576510; GU576512; GU576514-GU57615; GU576517; GU576519; GU576521-GU576522; GU576524; GU576526-GU576527; GU576529; GU576531-GU576532; GU576534; GU576536-GU576540; GU585403–GU585443; (neuraminidase sequences) GU936490-GU936491. Scale bar indicates proportion of nucleotide substitutions per site.
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