Volume 16, Number 8—August 2010
CME ACTIVITY - Research
Correlation of Pandemic (H1N1) 2009 Viral Load with Disease Severity and Prolonged Viral Shedding in Children
Table 1
Demographic data for 581 patients with RT-PCR–confirmed pandemic (H1N1) 2009 virus infection, Taiwan*
Demographic variable |
No. (%) patients† |
---|---|
Sex, M/F | 337/244 |
Age, y | |
Median | 10.1 |
Range | 0.38–78.8 |
<4 | 49 (8.4) |
>4 to <7 | 87 (15.0) |
>7 to <13 | 256 (44.1) |
>13 to <18 | 130 (22.4) |
>18 to <50 | 54 (9.3) |
>50 |
5 (0.9) |
Days after onset of fever | |
0 (no fever) | 8 (1.4) |
1 | 354 (60.9) |
2 | 148 (25.5) |
3 | 49 (8.4) |
4 | 12 (2.1) |
5 | 7 (1.2) |
>6 |
3 (0.5) |
Disease severity | |
URI† | 518 (89.2) |
Bronchitis | 43 (7.4) |
Pneumonia | 17 (2.9) |
Meningoencephalitis |
3 (0.5) |
Virus load from first throat swab, log10 copies/mL | |
<1.0 | 6 (1.0) |
1.0– 2.0 | 47 (8.1) |
>2.0 –3.0 | 80 (13.8) |
>3.0 –4.0 | 170 (29.3) |
>4.0–5.0 | 190 (32.7) |
>5.0– 6.0 | 83 (14.3) |
>6.0 | 5 (0.9) |
*RT-PCR, reverse transcription–PCR; URI, upper respiratory tract infection.
†Except as indicated.