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Volume 17, Number 10—October 2011
Dispatch

Seroconversion to Pandemic (H1N1) 2009 Virus and Cross-Reactive Immunity to Other Swine Influenza Viruses

Ranawaka A.P.M. Perera, Steven Riley, Siu K. Ma, Hua-Chen Zhu, Yi Guan, and Joseph S.M. PeirisComments to Author 
Author affiliations: The University of Hong Kong, Hong Kong Special Administrative Region, People’s Republic of China (R.A.P.M. Perera, S.K. Ma, H.-C. Zhu, Y. Guan, J.S.M. Peiris); Imperial College, London, UK (S. Riley)

Main Article

Figure

Neutralizing antibody titers to subtype H1 swine influenza viruses of the classical swine, North American triple reassortant, and Eurasian avian-like swine lineages in baseline (prepandemic [pre]) and convalescent-phase (postpandemic [post]) serum samples from 28 persons who seroconverted to pandemic (H1N1) 2009 infection, Hong Kong. Complete details on the serologic study cohort from which this subset is drawn are from (4). The pandemic A/California/4/2009 (H1N1) and seasonal influenza A/HK/400

Figure. Neutralizing antibody titers to subtype H1 swine influenza viruses of the classical swine, North American triple reassortant, and Eurasian avian-like swine lineages in baseline (prepandemic [pre]) and convalescent-phase (postpandemic [post]) serum samples from 28 persons who seroconverted to pandemic (H1N1) 2009 infection, Hong Kong. Complete details on the serologic study cohort from which this subset is drawn are from (4). The pandemic A/California/4/2009 (H1N1) and seasonal influenza A/HK/400599/2008 (H1N1) viruses were used as controls. Orange lines indicate geometric mean titer; green error bars indicate 95% confidence intervals. *p<0.05; †p<0.01.

Main Article

References
  1. Hancock  K, Veguilla  V, Lu  X, Zhong  W, Butler  EN, Sun  H, Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med. 2009;361:1945–52. DOIPubMedGoogle Scholar
  2. Brockwell-Staats  C, Webster  RG, Webby  RJ. Diversity of influenza viruses in swine and the emergence of a novel human pandemic influenza A (H1N1). Influenza Other Respi Viruses. 2009;3:207–13. DOIPubMedGoogle Scholar
  3. Vijaykrishna  D, Smith  GDJ, Pybus  OG, Zhu  H, Bhatt  S, Poon  LLM, Long-term evolution and transmission dynamics of swine influenza A virus. Nature. 2011;473:519–22. DOIPubMedGoogle Scholar
  4. Riley  S, Kwok  KO, Wu  KM, Ning  DY, Cowling  BJ, Wu  JT, Epidemiological characteristics of 2009 (H1N1) pandemic influenza based on paired sera from a longitudinal community cohort study. PLoS Med. 2011;8:e1000442 .DOIPubMedGoogle Scholar
  5. Hung  IF, To  KK, Lee  CK, Lin  CK, Chan  JF, Tse  H, Effect of clinical and virological parameters on the level of neutralizing antibody against pandemic influenza A virus H1N1 2009. Clin Infect Dis. 2010;51:274–9. DOIPubMedGoogle Scholar

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Page created: September 26, 2011
Page updated: September 26, 2011
Page reviewed: September 26, 2011
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