TY - JOUR AU - Drexler, Jan Felix AU - Corman, Victor Max AU - Wegner, Tom AU - Tateno, Adriana Fumie AU - Zerbinati, Rodrigo Melim AU - Gloza-Rausch, Florian AU - Seebens, Antje AU - Müller, Marcel AU - Drosten, Christian T1 - Amplification of Emerging Viruses in a Bat Colony T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 3 SP - 449 SN - 1080-6059 AB - Bats host noteworthy viral pathogens, including coronaviruses, astroviruses, and adenoviruses. Knowledge on the ecology of reservoir-borne viruses is critical for preventive approaches against zoonotic epidemics. We studied a maternity colony of Myotis myotis bats in the attic of a private house in a suburban neighborhood in Rhineland-Palatinate, Germany, during 2008, 2009, and 2010. One coronavirus, 6 astroviruses, and 1 novel adenovirus were identified and monitored quantitatively. Strong and specific amplification of RNA viruses, but not of DNA viruses, occurred during colony formation and after parturition. The breeding success of the colony was significantly better in 2010 than in 2008, in spite of stronger amplification of coronaviruses and astroviruses in 2010, suggesting that these viruses had little pathogenic influence on bats. However, the general correlation of virus and bat population dynamics suggests that bats control infections similar to other mammals and that they may well experience epidemics of viruses under certain circumstances. KW - Zoonoses KW - bats KW - coronavirus KW - astrovirus KW - adenovirus KW - viruses KW - zoonotic risk assessment KW - reservoir ecology KW - research KW - Germany DO - 10.3201/eid1703.100526 UR - https://wwwnc.cdc.gov/eid/article/17/3/10-0526_article ER - End of Reference