TY - JOUR AU - Perri, Bianca R. AU - Proops, Douglas AU - Moonan, Patrick K. AU - Munsiff, Sonal S. AU - Kreiswirth, Barry N. AU - Kurepina, Natalia AU - Goranson, Christopher AU - Ahuja, Shama D. T1 - Mycobacterium tuberculosis Cluster with Developing Drug Resistance, New York, New York, USA, 2003–2009 T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 3 SP - 372 SN - 1080-6059 AB - In 2004, identification of patients infected with the same Mycobacterium tuberculosis strain in New York, New York, USA, resulted in an outbreak investigation. The investigation involved data collection and analysis, establishing links between patients, and forming transmission hypotheses. Fifty-four geographically clustered cases were identified during 2003–2009. Initially, the M. tuberculosis strain was drug susceptible. However, in 2006, isoniazid resistance emerged, resulting in isoniazid-resistant M. tuberculosis among 17 (31%) patients. Compared with patients with drug-susceptible M. tuberculosis, a greater proportion of patients with isoniazid-resistant M. tuberculosis were US born and had a history of illegal drug use. No patients named one another as contacts. We used patient photographs to identify links between patients. Three links were associated with drug use among patients infected with isoniazid-resistant M. tuberculosis. The photographic method would have been more successful if used earlier in the investigation. Name-based contact investigation might not identify all contacts, particularly when illegal drug use is involved. KW - Tuberculosis and other mycobacteria KW - Mycobacterium tuberculosis KW - bacteria KW - drug resistance KW - disease outbreak KW - contact tracing KW - molecular epidemiology KW - New York City KW - research KW - New York KW - USA KW - United States DO - 10.3201/eid1703.101002 UR - https://wwwnc.cdc.gov/eid/article/17/3/10-1002_article ER - End of Reference