TY - JOUR AU - Accou-Demartin, Marie AU - Gaborieau, Valérie AU - Song, Yajun AU - Roumagnac, Philippe AU - Marchou, Bruno AU - Achtman, Mark AU - Weill, François-Xavier T1 - Salmonella enterica Serotype Typhi with Nonclassical Quinolone Resistance Phenotype T2 - Emerging Infectious Disease journal PY - 2011 VL - 17 IS - 6 SP - 1091 SN - 1080-6059 AB - We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure. KW - Salmonella KW - typhoid fever KW - ciprofloxacin KW - treatment failure KW - gyrB KW - bacteria KW - antimicrobial resistance KW - expedited KW - dispatch KW - France KW - India KW - United Kingdom KW - United States KW - Pakistan KW - Bangladesh KW - Tunisia KW - French Guiana DO - 10.3201/eid1706.101242 UR - https://wwwnc.cdc.gov/eid/article/17/6/10-1242_article ER - End of Reference