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Volume 17, Number 7—July 2011

Severe Plasmodium knowlesi Malaria in a Tertiary Care Hospital, Sabah, Malaysia

Timothy William, Jayaram Menon, Giri S. Rajahram, Leslie Chan, Gordon Ma, Samantha Donaldson, Serena Khoo, Charlie Fredrick, Jenarun Jelip, Nicholas M. Anstey, and Tsin Wen YeoComments to Author 
Author affiliations: Author affiliations: Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysian Borneo (T. William, J. Menon, G. Rajahram, L. Chan, G. Ma, S. Donaldson, S. Khoo, C. Fredrick); Department of Health, Kota Kinabalu, Malaysia (J. Jelip); Menzies School of Health Research and Charles Darwin University, Darwin, Northern Territory, Australia (N.M. Anstey, T.W. Yeo); Royal Darwin Hospital, Darwin (N.M. Anstey, T.W. Yeo)

Main Article

Table 1

Baseline demographic characteristics and clinical features of patients with severe and uncomplicated Plasmodium knowlesi malaria, Sabah, Malaysia, 2007–2009

Characteristic Uncomplicated disease, n = 34 Severe disease, n = 22
Mean age, y* (range) 37 (20–66) 57 (22–84)
No. (%) female patients† 3 (8.8) 8 (36.3)
Self-reported previous malaria, no. patients 1 0
History of chronic illness, % 18 10
Mean duration of illness, d (range)
5.0 (1–30)
5.2 (2–7)
Fever, % 100 96
Headache, % 62 57
Diarrhea, %
Physical findings
Mean temperature (range) 38.2°C (36.5–41°C) 37.6°C (36.7–39.2 °C)
Mean respiratory rate, breaths/min* (range) 20 (14–26) 26 (15–50)
Mean pulse rate, beats/min (range) 95 (69–151) 100 (76–130)
Mean arterial pressure, mm Hg (range)* 85 (61–106) 74 (42–106)
Mean oxygen saturation, % (range)* 98 (92–100), n = 20 88 (56–100), n = 17

*p<0.05 by Mann Whitney U test.
†p<0.05 by χ2 test.

Main Article

Page created: August 15, 2011
Page updated: August 15, 2011
Page reviewed: August 15, 2011
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