Volume 17, Number 7—July 2011
Research
Severe Plasmodium knowlesi Malaria in a Tertiary Care Hospital, Sabah, Malaysia
Timothy William, Jayaram Menon, Giri S. Rajahram, Leslie Chan, Gordon Ma, Samantha Donaldson, Serena Khoo, Charlie Fredrick, Jenarun Jelip, Nicholas M. Anstey, and Tsin Wen Yeo
Table 1
Baseline demographic characteristics and clinical features of patients with severe and uncomplicated Plasmodium knowlesi malaria, Sabah, Malaysia, 2007–2009
| Characteristic | Uncomplicated disease, n = 34 | Severe disease, n = 22 |
|---|---|---|
| Mean age, y* (range) | 37 (20–66) | 57 (22–84) |
| No. (%) female patients† | 3 (8.8) | 8 (36.3) |
| Self-reported previous malaria, no. patients | 1 | 0 |
| History of chronic illness, % | 18 | 10 |
| Mean duration of illness, d (range) |
5.0 (1–30) |
5.2 (2–7) |
| Symptoms | ||
| Fever, % | 100 | 96 |
| Headache, % | 62 | 57 |
| Diarrhea, % |
21 |
24 |
| Physical findings | ||
| Mean temperature (range) | 38.2°C (36.5–41°C) | 37.6°C (36.7–39.2 °C) |
| Mean respiratory rate, breaths/min* (range) | 20 (14–26) | 26 (15–50) |
| Mean pulse rate, beats/min (range) | 95 (69–151) | 100 (76–130) |
| Mean arterial pressure, mm Hg (range)* | 85 (61–106) | 74 (42–106) |
| Mean oxygen saturation, % (range)* | 98 (92–100), n = 20 | 88 (56–100), n = 17 |
*p<0.05 by Mann Whitney U test.
†p<0.05 by χ2 test.
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Page updated: August 15, 2011
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