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Volume 18, Number 3—March 2012
Dispatch

Drug-Resistant Tuberculosis in Zhejiang Province, China, 1999–2008

Xiaomeng Wang, Qian Fu, Zhijun Li, Songhua Chen, Zhengwei Liu, Hugh Nelson, Qun Yang, Zhongwei JiaComments to Author , and Christopher Dye
Author affiliations: Center for TB Control in Zhejiang, Hangzhou, People’s Republic of China (X. Wang, S. Chen, Z. Liu); Capital Medical University, Beijing, People’s Republic of China (Q. Fu, Q. Yang); National Research Institute of Food and Fermentation Industries, Beijing (Z. Li); International SOS Clinic, Shekou, People’s Republic of China (H. Nelson); Peking University, Beijing (Z. Jia); World Health Organization, Geneva, Switzerland (C. Dye)

Main Article

Table 2

Factors associated with resistance to tuberculosis drugs, Zhejiang Province, China, 1999–2008*

Characteristic Coefficient OR (95% CI) p value
Model 1: Risk factors associated with resistance to isoniazid
    Constant −4.10 0.02
    Year 0.23 1.26 (0.87–1.84) 0.221
    Rifampin 2.99 19.91 (12.91–30.70) <0.001
    Age 0–14 years 0.89 2.43 (0.20–34.90) 0.51
    Age 15–64 years −0.49 0.61 (0.40–0.94) <0.05
    Sex 0.16 1.17 (0.80–1.71) 0.43
    Re-treatment 0.62 1.85 (1.24–2.76) <0.005
Model 2: Risk factors associated with resistance to rifampin
    Constant −3.33 0.10 <0.001
    Year −0.53 0.59 (0.38–0.93) <0.05
    Isoniazid 2.99 19.85 (12.92–30.51) <0.001
    Age 0–14 year −1.74 0.18 (0.02–1.29) 0.09
    Age 15–64 year −0.05 1.02 (0.62–1.66) 0.95
    Sex −0.30 0.73 (0.47–1.16) 0.19
    Re-treatment 1.84 6.29 (4.15–9.53) <0.001
Model 3: Risk factors associated with MDR TB
    Constant −2.78 0.62 <0.001
    Year −0.16 0.86 (0.61–1.21) 0.384
    Age 0–14 year −0.69 0.52 (0.06–4.36) 0.56
    Age 15–64 year −0.45 0.62 (0.40–0.96) <0.05
    Sex −0.17 0.86 (0.58–1.23) 0.37
    Re-treatment 2.20 9.01 (6.39–12.68) <0.001

*Reference groups are >65 years for age, female for sex, and new for re-treatment. OR, odds ratio; MDR TB, multidrug-resistant tuberculosis.

Main Article

Page created: February 16, 2012
Page updated: February 16, 2012
Page reviewed: February 16, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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