TY - JOUR AU - Chen, Enfu AU - Cauchemez, Simon AU - Donnelly, Christl AU - Zhou, Lei AU - Feng, Luzhao AU - Xiang, Nijuan AU - Zheng, Jiandong AU - Ye, Min AU - Huai, Yang AU - Liao, Qiaohong AU - Peng, Zhibin AU - Feng, Yunxia AU - Jiang, Hui AU - Yang, Weizhong AU - Wang, Yu AU - Ferguson, Neil AU - Feng, Zijian T1 - Transmission Dynamics, Border Entry Screening, and School Holidays during the 2009 Influenza A (H1N1) Pandemic, China T2 - Emerging Infectious Disease journal PY - 2012 VL - 18 IS - 5 SP - 758 SN - 1080-6059 AB - Pandemic influenza A (H1N1) 2009 virus spread rapidly around the world in 2009. We used multiple data sources from surveillance systems and specific investigations to characterize the transmission patterns of this virus in China during May–November 2009 and analyze the effectiveness of border entry screening and holiday-related school closures on transmission. In China, age distribution and transmission dynamic characteristics were similar to those in Northern Hemisphere temperate countries. The epidemic was focused in children, with an effective reproduction number of ≈1.2–1.3. The 8 days of national holidays in October reduced the effective reproduction number by 37% (95% credible interval 28%–45%) and increased underreporting by ≈20%–30%. Border entry screening detected at most 37% of international travel–related cases, with most (89%) persons identified as having fever at time of entry. These findings suggest that border entry screening was unlikely to have delayed spread in China by >4 days. KW - transmission KW - school closure KW - border screening KW - influenza A KW - pandemic (H1N1) 2009 KW - China KW - influenza KW - viruses KW - People’s Republic of China DO - 10.3201/eid1805.110356 UR - https://wwwnc.cdc.gov/eid/article/18/5/11-0356_article ER - End of Reference