Figure 1. . . Epidemiology of invasive encapsulated Haemophilus influenzae disease, England and Wales, 2000–2009. Serotypes Hib, Hie, and Hif predominated, with Hib incidence dropping rapidly after re-introduction of a whole-cell pertussis–containing Hib vaccine in 2002, a Hib booster campaign for toddlers in 2003, and a routine 12-month Hib booster in 2006. During the period shown, only 6 cases of Hia and 2 each of Hic and Hid were reported. Error bars indicate 95% CIs.