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Volume 18, Number 5—May 2012
Dispatch

Human Infections with Novel Reassortant Influenza A(H3N2)v Viruses, United States, 2011

Stephen Lindstrom, Rebecca Garten, Amanda Balish, Bo Shu, Shannon Emery, LaShondra Berman, Nathelia Barnes, Katrina Sleeman, Larisa Gubareva, Julie Villanueva, and Alexander KlimovComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S. Lindstrom, R. Garten, A. Balish, B. Shu, S. Emery, L. Berman, K. Sleeman, L. Gubareva, J. Villanueva, A. Klimov); Battelle, Atlanta (N. Barnes)

Main Article

Table 1

Results of analysis of viral RNA isolated from original clinical samples from persons with influenza A(H3N2)v virus infection, United States, 2011*

Influenza virus strain Contact with swine (11–13) Specimen collection date Specimen type rRT-PCR–positive results† Genes sequenced‡
A/Indiana/08/2011 No Jul 24 NPS InfA, H3, pdmInfA Full genome
A/Pennsylvania/09/2011 Indirect Aug 20 NPS InfA, H3, pdmInfA Full PB2, PB1, HA, NP, NA, M, NS, partial PA
A/Pennsylvania/10/2011 Direct Aug 26 NPS InfA Full NS, partial HA, M, NA
A/Pennsylvania/11/2011 Indirect Aug 25 NPS InfA, H3, pdmInfA Full PA, NP, NA, M NS, partial PB2, PB1, HA
A/Maine/06/2011 Direct Oct 10 NPS InfA, H3, pdmInfA Full genome
A/Indiana/10/2011§ Direct Oct 22 Cell culture InfA, H3, pdmInfA Full genome
A/Maine/07/2011 Direct Oct 24 NPS InfA Partial HA, M, NS
A/Iowa/07/2011 No Nov 14 NPW InfA, H3, pdmInfA Full PB2, PB1, PA, NP, NA, M, NS, partial HA
A/Iowa/08/2011 No Nov 14 NS InfA, H3, pdmInfA Full genome
A/Iowa/09/2011 No Nov 14 NS InfA, H3, pdmInfA Full genome
A/West Virginia/06/2011 No Nov 21 NW InfA, H3, pdmInfA Full genome
A/West Virginia/07/2011 No Dec 07 NPS InfA Partial HA, NA, M

*Influenza A(H3N2)v, influenza virus variant identified in humans; rRT-PCR, real-time reverse transcription PCR; NPS, nasopharyngeal swab; PB, polymerase basic protein; HA, hemagglutinin; NP nucleoprotein; NA, neuraminidase; M, matrix protein; NS, nonstructural protein; PA, polymerase acidic protein; NPW, nasopharyngeal wash; NS, nasal swab.
†Results obtained by using the Centers for Disease Control and Prevention Human Influenza Virus Real-Time RT-PCR Diagnostic Panel.
‡Sequences available from GenBank and the Technical Appendix Table.
§This patient was >18 years of age; all others were <18.

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Page created: April 17, 2012
Page updated: April 17, 2012
Page reviewed: April 17, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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