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Volume 18, Number 7—July 2012
Dispatch

Seroconversion to Seasonal Influenza Viruses after A(H1N1)pdm09 Virus Infection, Quebec, Canada

Mariana Baz, Jesse Papenburg, Marie-Eve Hamelin, Manale Ouakki, Danuta M. Skowronski, Gaston De Serres, and Guy BoivinComments to Author 
Author affiliations: Author affiliations: Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada (M. Baz, J. Papenburg, M.-E. Hamelin, G. Boivin); Laval University, Quebec City (M. Baz, J. Papenburg, M.-E. Hamelin, G. Boivin); Institut National de Santé Publique du Quebec, Quebec (M. Ouakki, G. De Serres); British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada (D.M. Skowronski)

Main Article

Table

Clinical features and microneutralization antibody titers against influenza A(H1N1)pdm09 and seasonal influenza A viruses of persons who seroconverted to >2 influenza viruses, Quebec City, Quebec, Canada, 2009*

Participant no./age, y RT-PCR for A(H1N1) pdm09 Titers, acute phase/convalescent phase (-fold increase)
Symptoms
A/Quebec/147023/ 2009; A(H1N1)pdm09 A/Brisbane/59/ 2007 (H1N1) A/New Caledonia/ 99 (H1N1) A/Panama/2007/99 (H3N2)
ARI ILI
39A/7 + + + <10/160 (16) <10/320 (32) <10/160 (16) 320/160 (0)
39C/11 + + + <10/40 (4) 10/160 (16) <10/40 (4) 2,560/2,560 (0)
49A/28 + + + <10/160 (16) 40/160 (4) <10/20 (2) 320/320 (0)
49B/23 + + + <10/640 (64) <10/160 (16) 40/160 (4) 40/40 (0)
55F/7 + + + <10/40 (4) 10/40 (4) 20/80 (4) 10/10 (0)
16C/7 + + + <10/80 (8) 160/320 (2) 40/160 (4) 80/80 (0)
56A/12 + + + <10/40 (4) 80/320 (4) 40/80 (2) 2,560/2,560 (0)
65B/40 + + + <10/320 (32) <10/20 (2) 10/40 (4) 320/320 (0)
03E/17 + + + <10/80 (8) 40/80 (2) 160/160 (0) 640/5120 (8)
10B/14 + + + <10/80 (8) 20/20 (0) 80/320 (4) 640/640 (0)
11C/61† + + + <10/1,280 (128) 40/160 (4) 160/160 (0) 320/1,280 (4)
44B/9 + + + <10/<80 (8) 1,280/640 (0) 1,280/1,280 (0) 160/640 (4)
44C/44 + <10/20 (2) 10/80 (8) 80/80 (0) 160/640 (4)
58A/13 + + + <10/80 (8) <10/20 (2) 10/20 (2) 1,280/5,120 (4)
58B/43 + + <10/160 (16) <10/10 (0) <10/<10 (0) 20/160 (8)

*RT-PCR, reverse transcription PCR; ARI, acute respiratory illness (i.e., presence of ≥2 of the following signs/symptoms: fever [≥37.8°C] or feverishness, cough, sore throat, or rhinorrhea); ILI, influenza-like illness (i.e., fever and cough and/or sore throat); +, positive; –, negative.
†Received seasonal vaccine in 2008–09.

Main Article

Page created: June 13, 2012
Page updated: June 13, 2012
Page reviewed: June 13, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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