TY - JOUR AU - Asidi, Alex AU - N’Guessan, Raphael AU - Akogbeto, Martin AU - Curtis, Chris AU - Rowland, Mark T1 - Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin T2 - Emerging Infectious Disease journal PY - 2012 VL - 18 IS - 7 SP - 1101 SN - 1080-6059 AB - Pyrethroid resistance is becoming widespread in Anopheles gambiae mosquitoes, coinciding with expanded use of insecticide-treated nets (ITNs) throughout Africa. To investigate whether nets in use are still protective, we conducted household trials in northern and southern Benin, where An. gambiae mosquitoes are susceptible and resistant, respectively, to pyrethroids. Rooms were fitted with window traps and monitored for mosquito biting and survival rates before and after the nets were treated with pyrethroid. Sleeping under an ITN in the location with resistant mosquitoes was no more protective than sleeping under an untreated net, regardless of its physical condition. By contrast, sleeping under an ITN in the location with susceptible mosquitoes decreased the odds of biting by 66%. ITNs provide little or no protection once the mosquitoes become resistant and the netting acquires holes. Resistance seriously threatens malaria control strategies based on ITN. KW - Anopheles gambiae KW - pyrethroid KW - insecticide resistance KW - insecticide treated bed nets KW - Benin KW - malaria KW - mosquitoes KW - parasites DO - 10.3201/eid1807.120218 UR - https://wwwnc.cdc.gov/eid/article/18/7/12-0218_article ER - End of Reference