Volume 18, Number 8—August 2012
Chloroquine-Resistant Malaria in Travelers Returning from Haiti after 2010 Earthquake
|Characteristics||Before earthquake, n = 49||After earthquake, n = 30|
|In vitro analysis||n = 24||n = 10|
|IC50 for chloroquine, nmol/L (mean 95% CI)||27 (23–31)||35 (12–105)*|
|No. isolates resistant†|
|Molecular marker analysis, no. (%) isolates||n = 29||n = 19|
*The 2 resistant isolates are included with an IC50 of 506 nmol/L and 708 nmol/L. IC50, 50% inhibitory concentration.
†A threshold of IC50 = 100 nmol/L is applied to determine resistant isolates (consensus between the laboratories in France and Canada) and in vitro susceptibility (IC50) for the isolates from patients returning from Haiti.
1Members of the French National Reference Center for Imported Malaria Study who contributed data are listed at the end of this article.