Volume 18, Number 8—August 2012
Dispatch
Autochthonous Infections with Hepatitis E Virus Genotype 4, France
Philippe Colson
, Pauline Romanet, Valérie Moal, Patrick Borentain, Raj Purgus, Alban Benezech, Anne Motte, and René Gérolami
, Pauline Romanet, Valérie Moal, Patrick Borentain, Raj Purgus, Alban Benezech, Anne Motte, and René Gérolami
Table 1
Epidemiologic and virological findings for case-patients and contacts with HEV infection, Marseille, France, January–March 2011*
| Case-patients and contacts, by ID no. | Day obtained, serum sample (retrospectively tested sample) | Anti-HEV IgG EIA result† | Anti-HEV IgM result, by testing method |
HEV RNA in serum (Ct) | HEV genotype | ||
|---|---|---|---|---|---|---|---|
| EIA† | Rapid test‡ | Immunoblot | |||||
| 1 | Feb18 | 10.3 | 14.2 | Positive | Positive | Positive (29) | 4 |
| 1a§ | Mar 2 | 11.4 | 0.2 | Negative | Not tested | Positive (38) | NA |
| 1a§ | Mar 16 | >10.0 | 2.0 | Not tested | Borderline | Negative | NA |
| 1b¶ | Mar 2 | Negative | Negative | Negative | Negative | Negative | NA |
| 2 | Mar 21 (Feb 7) | 11.2 | 15.6 | Positive | Positive | Positive (28) | 4 |
| 2a# | Mar 21 | 6.3 | 15.6 | Positive | Positive | Negative | NA |
| 2b** | Mar 21 | 0.1 | Negative | Negative | Negative | Negative | NA |
| 3 | Jan 4 | 10.7 | 16.6 | Positive | Not tested | Positive (27) | 3f |
| 4 | Feb 3 (Jan 6) | 5.2 | 6.3 | Weakly reactive†† | Positive | Positive (26) | 3c |
| 5‡‡ | Feb 3 | 0.1 | 1.6 | Weakly reactive | Negative | Positive (31) | 3f |
| 6 | Mar 1 | 11 | 14 | Positive | Positive | Positive (38) | NA |
| 7 | Mar 2 | 10.6 | 15.1 | Positive | Negative | Positive (27) | 3c |
| 8‡‡ | Mar 9 | 11.1 | 14.9 | Positive | Not tested | Positive (28) | 3c |
| 9 | Mar 18 | 10.5 | 16.4 | Positive | Not tested | Positive (28) | 3f |
| 10‡‡ | Mar 21 | 0.3 | 15.6 | Positive | Not tested | Positive (24) | 3c |
| 11 | Mar 23 | 1.2 | 13.8 | Positive | Positive | Positive (27) | 3f |
*Italics indicate results for contacts of case-patients. HEV, hepatitis E virus; ID, identification; EIA, enzyme immunoassay; Ct, cycle threshold; NA, not applicable.
†EIA score represents test/cutoff optical density ratios.
‡An immunochromatographic rapid test.
§Contact (wife) of case-patient no. 1.
¶Contact (friend) of case-patient no. 1.
#Contact (friend) of case-patient no. 2.
**Contact (sister) of case-patient no. 2.
††Tested on a serum sample collected on March 3, 2011.
‡‡Kidney transplant recipient.
Page created: July 23, 2012
Page updated: July 23, 2012
Page reviewed: July 23, 2012
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