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Volume 18, Number 9—September 2012

Multiple Synchronous Outbreaks of Puumala Virus, Germany, 2010

Jakob Ettinger1, Jorg Hofmann1, Martin Enders, Friedemann Tewald, Rainer M. Oehme, Ulrike M. Rosenfeld, Hanan Sheikh Ali, Mathias Schlegel, Sandra Essbauer, Anja Osterberg, Jens Jacob, Daniela Reil, Boris Klempa, Rainer G. Ulrich, and Detlev H. KrugerComments to Author 
Author affiliations: Charité Medical School and Labor Berlin Charité-Vivantes GmbH, Berlin, Germany (J. Ettinger, J. Hofmann, B. Klempa, D.H. Kruger); Institute of Virology, Infectious Diseases, and Epidemiology, Stuttgart, Germany (M. Enders, F. Tewald); Baden-Wuerttemberg State Health Office, Stuttgart (R.M. Oehme); Friedrich-Loeffler Institut, Greifswald, Germany (U.M. Rosenfeld, H.S. Ali, M. Schlegel, R.G. Ulrich); Bundeswehr Institute of Microbiology, Munich, Germany (S. Essbauer, A. Osterberg); Institute for Plant Protection in Horticulture and Forestry, Münster, Germany (J. Jacob, D. Reil); and Slovak Academy of Sciences, Bratislava, Slovakia (B. Klempa)

Main Article


Amino acid and nucleotide sequence identity rates within and between different Puumala virus clades, Germany*

Clade No. samples % Amino acid identity† % Nucleotide identity† % Identity
SJ (1) BF (2) SF (3) NEH (4) TF (5) ML (6)
SJ (1) 30 97.9 96.2 91.5 90.3 91.5 90.9 92.6
BF (2) 24 99.3 97.9 85.7 95.2 96.3 95.2 96.8
SF (3 15 99.3 97.0 84.0 87.2 96.0 93.7 95.4
NEH (4) 4 99.3 96.9 83.9 85.8 86.7 95.4 97.1
TF (5) 13 99.4 98.2 81.3 84.4 83.3 84.8 97.7
ML (6) 9 100 98.7 83.1 84.7 83.1 84.4 89.0

*Sequences of the 504-bp small segment were compared. Values above the diagonal indicate amino acid identity, and values below the diagonal indicate nucleotide identity. Numbers in parentheses indicate outbreak regions as shown in Figure 1 and Figure 2. SJ, Swabian Jura; BF, Bavarian Forest; SF, Spessart Forest; NEH, North East Hesse; TF, Teutoburg Forest; ML, Münsterland.
†Within each clade.

Main Article

1These authors contributed equally to this article.

Page created: August 16, 2012
Page updated: September 05, 2012
Page reviewed: September 05, 2012
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