TY - JOUR AU - Rahman, Sohayati AU - Hassan, Latiffah AU - Epstein, Jonathan AU - Mamat, Zaini AU - Yatim, Aziz AU - Hassan, Sharifah AU - Field, Hume AU - Hughes, Tom AU - Westrum, Justin AU - Naim, M.S. AU - Suri, Arshad AU - Jamaluddin, A. Aziz AU - Daszak, Peter T1 - Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia T2 - Emerging Infectious Disease journal PY - 2013 VL - 19 IS - 1 SP - 51 SN - 1080-6059 AB - We conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We observed a consistently higher NiV risk (odds ratio 3.9) and seroprevalence (32.8%) for P. vampyrus than P. hypomelanus (11.1%) bats. A 3-year longitudinal study of P. hypomelanus bats indicated nonseasonal temporal variation in seroprevalence, evidence for viral circulation within the study period, and an overall NiV seroprevalence of 9.8%. The seroprevalence fluctuated over the study duration between 1% and 20% and generally decreased during 2004–2006. Adult bats, particularly pregnant, with dependent pup and lactating bats, had a higher prevalence of NiV antibodies than juveniles. Antibodies in juveniles 6 months–2 years of age suggested viral circulation within the study period. KW - Nipah virus KW - viruses KW - risk factors KW - seroprevalence KW - infection KW - distribution KW - bats KW - Pteropid bats KW - reservoir hosts KW - Malaysia KW - Pteropus vampyrus KW - Pteropus hypomelanus DO - 10.3201/eid1901.120221 UR - https://wwwnc.cdc.gov/eid/article/19/1/12-0221_article ER - End of Reference