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Volume 19, Number 11—November 2013
CME ACTIVITY - Synopsis

Tropheryma whipplei Endocarditis

Florence Fenollar, Marie Célard, Jean-Christophe Lagier, Hubert Lepidi, Pierre-Edouard Fournier, and Didier RaoultComments to Author 
Author affiliations: Aix-Marseille Université, Marseille, France (F. Fenollar, J.-C. Lagier, H. Lepidi, P.-E. Fournier, D. Raoult); Assistance Publique Hopitaux de Marseille, Marseille (F. Fenollar, J.-C. Lagier, P.-E. Fournier, D. Raoult); Groupement Hospitalier Est, Bron, France (M. Célard)

Main Article

Table 1

Epidemiologic and clinical characteristics of 28 patients with Tropheryma whipplei endocarditis*

Patient
(reference) Area of origin Age, y IS Cardiac history Arthralgia duration, y Weight loss Cardiac symptoms Fever Involved valves Vegetation
1 PACA 80 N PM Y (15) N HF and AIS N AV Y
2 Corsica† 58 N N Y (8) N HF Y AV+MV N
3 Rhône-Alpes 54 N N Y (3) Y HF Y AV Y
4 Rhône-Alpes 45 N BAV N N Stroke Y AV Y
5 Rhône-Alpes 56 N CS N N HF Y AV Y
6 PACA 59 Y N Y (35) N HF N AV N
7 Pays de la Loire 50 N N Y (NA) N HF N AV+MV Y
8 Picardie 51 N N N N Stroke N AV Y
9 PACA 79 N AVB Y N HF N AV Y
10 Lorraine 50 N N N N HF N MV N
11 Rhône-Alpes 62 N N Y N HF N AV Y
12 PACA 58 N BAV Y Y HF Y AV Y
13 (2) Rhône-Alpes 71 N N N N HF N AV Y
14 (18) Rhône-Alpes 57 Y N Y (4) N HF+PAE Y AV N
15 (2) Poitou-Charentes 68 N N N N HF Y AV Y
16 (2) Pays de la Loire 48 N AVI Y (NA) N HF Y AV Y
17 (19) Languedoc-Roussillon 70 Y N Y (27) N HF Y AV Y
18 (2) Pays de la Loire 71 N MVI Y (NA) N HF Y MV Y
19 (2) Pays de la Loire 57 Y N Y (10) Y HF Y AV+MV N
20 (2) Rhône-Alpes 67 N N Y (4) N Stroke N AV N
21 (2) Rhône-Alpes 51 Y N Y (6) N PAE N AV+TV Y
22 (2) Pays de la Loire 58 N AAR Y (NA) N PAE N AV Y
23 (2) Rhône-Alpes 60 Y N Y (2) N HF N AV+MV Y
24 (2) Rhône-Alpes 61 N AAR Y (4) N Stroke N AV+MV Y
25 (2) Rhône-Alpes 63 N N Y (3) N PAE+stroke N AV Y
26 (5) Canada 42 N AAR N Y HF N AV+MV Y
27 (2) Rhône-Alpes 40 Y AAR Y (5) N HF N AV Y
28 (2) Rhône-Alpes 55 N N Y (5) Y Stroke N MV Y

*All patients were male, and none had diarrhea. IS, immunosuppressive therapy; PACA, Provence-Alpes-Côte-d’Azur; N, no; PM, pacemaker; Y, yes; HF; heart failure; AIS, acute ischemic stroke; AV, aortic valve; MV, mitral valve; BAV, bicuspid aortic valve; CS, coronary stent; AVB, aortic valve bioprosthesis; AVI, aortic valve insufficiency; MVI, mitral valve insufficiency; NA, not available; PAE, peripheral arterial embolism; AAR, acute articular rheumatism.
†This patient was from Poland but resided in Corsica for 8 years.

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Page created: October 28, 2013
Page updated: October 28, 2013
Page reviewed: October 28, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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