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Volume 19, Number 11—November 2013

Tropheryma whipplei Endocarditis

Florence Fenollar, Marie Célard, Jean-Christophe Lagier, Hubert Lepidi, Pierre-Edouard Fournier, and Didier RaoultComments to Author 
Author affiliations: Aix-Marseille Université, Marseille, France (F. Fenollar, J.-C. Lagier, H. Lepidi, P.-E. Fournier, D. Raoult); Assistance Publique Hopitaux de Marseille, Marseille (F. Fenollar, J.-C. Lagier, P.-E. Fournier, D. Raoult); Groupement Hospitalier Est, Bron, France (M. Célard)

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Table 1

Epidemiologic and clinical characteristics of 28 patients with Tropheryma whipplei endocarditis*

(reference) Area of origin Age, y IS Cardiac history Arthralgia duration, y Weight loss Cardiac symptoms Fever Involved valves Vegetation
1 PACA 80 N PM Y (15) N HF and AIS N AV Y
2 Corsica† 58 N N Y (8) N HF Y AV+MV N
3 Rhône-Alpes 54 N N Y (3) Y HF Y AV Y
4 Rhône-Alpes 45 N BAV N N Stroke Y AV Y
5 Rhône-Alpes 56 N CS N N HF Y AV Y
6 PACA 59 Y N Y (35) N HF N AV N
7 Pays de la Loire 50 N N Y (NA) N HF N AV+MV Y
8 Picardie 51 N N N N Stroke N AV Y
10 Lorraine 50 N N N N HF N MV N
11 Rhône-Alpes 62 N N Y N HF N AV Y
13 (2) Rhône-Alpes 71 N N N N HF N AV Y
14 (18) Rhône-Alpes 57 Y N Y (4) N HF+PAE Y AV N
15 (2) Poitou-Charentes 68 N N N N HF Y AV Y
16 (2) Pays de la Loire 48 N AVI Y (NA) N HF Y AV Y
17 (19) Languedoc-Roussillon 70 Y N Y (27) N HF Y AV Y
18 (2) Pays de la Loire 71 N MVI Y (NA) N HF Y MV Y
19 (2) Pays de la Loire 57 Y N Y (10) Y HF Y AV+MV N
20 (2) Rhône-Alpes 67 N N Y (4) N Stroke N AV N
21 (2) Rhône-Alpes 51 Y N Y (6) N PAE N AV+TV Y
22 (2) Pays de la Loire 58 N AAR Y (NA) N PAE N AV Y
23 (2) Rhône-Alpes 60 Y N Y (2) N HF N AV+MV Y
24 (2) Rhône-Alpes 61 N AAR Y (4) N Stroke N AV+MV Y
25 (2) Rhône-Alpes 63 N N Y (3) N PAE+stroke N AV Y
26 (5) Canada 42 N AAR N Y HF N AV+MV Y
27 (2) Rhône-Alpes 40 Y AAR Y (5) N HF N AV Y
28 (2) Rhône-Alpes 55 N N Y (5) Y Stroke N MV Y

*All patients were male, and none had diarrhea. IS, immunosuppressive therapy; PACA, Provence-Alpes-Côte-d’Azur; N, no; PM, pacemaker; Y, yes; HF; heart failure; AIS, acute ischemic stroke; AV, aortic valve; MV, mitral valve; BAV, bicuspid aortic valve; CS, coronary stent; AVB, aortic valve bioprosthesis; AVI, aortic valve insufficiency; MVI, mitral valve insufficiency; NA, not available; PAE, peripheral arterial embolism; AAR, acute articular rheumatism.
†This patient was from Poland but resided in Corsica for 8 years.

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Page created: October 28, 2013
Page updated: October 28, 2013
Page reviewed: October 28, 2013
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