Volume 19, Number 3—March 2013
Dispatch
Prioritizing Tuberculosis Clusters by Genotype for Public Health Action, Washington, USA
Scott Lindquist
, Sheanne Allen, Kim Field, Smita Ghosh, Maryam B. Haddad, Masahiro Narita, and Eyal Oren
, Sheanne Allen, Kim Field, Smita Ghosh, Maryam B. Haddad, Masahiro Narita, and Eyal Oren
Table
Comparison of geospatial analysis results and expert panel priority status rankings for county-level genotype clusters of TB cases, Washington, USA, 2005–2010*
| County | Spoliogtype | 12-locus MIRU-VNTR | Period 1† |
Period 2† |
Key epidemiologic features‡ | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. cases | LLR | Expert priority | No. cases | LLR | Expert priority | |||||
| A | 000000000003771 | 223321153643 | 32 | 31.8 | High | 19 | 18.3 | High | H, SA | |
| 000000000003771 | 223325173533 | 17 | 0.1 | High | 8 | 0.4 | Low | FB | ||
| 677777477413771 | 254326223432 | 14 | 0.2 | Low | 14 | 0.1 | Low | FB | ||
| 703377400001771 | 227425113434 | 4 | 1.2 | Low | 6 | 2.9 | Low | FB, H | ||
| 000000000003771 | 223325153533 | 3 | 0.5 | Low | 1 | <0.01 | Low | FB | ||
| 000000000003771 | 223325163533 | 3 | 0.2 | Low | 7 | 1.7 | Low | FB, SA | ||
| 677777477413771 | 254326223422 | 6 | 1.3 | Low | 4 | 0.4 | Low | FB | ||
| 777000377760771 | 225125113322 | 3 | 0.6 | Low | 3 | 1.0 | Low | FB | ||
| 000000000003771 | 222325173543 | 9 | 2.4 | High | 3 | 0.1 | High | H, SA | ||
| 777777777760771 | 225125113322 | 3 | 0.7 | Low | 2 | 0.4 | Low | FB | ||
| 000000000003771 | 222325173533 | 7 | 2.6 | High | 8 | 2.3 | High | |||
| 000000000003771 | 223325173433 | 3 | 1.5 | Low | 1 | 0.2 | Low | FB | ||
| 000000000003771 | 223325133533 | 3 | 1.4 | Low | 0 | <0.01 | Low | FB | ||
| 000000000000000 | 223325123534 | 4 | 9.2 | High | 0 | <0.01 | Low | H, SA | ||
| 777776777620601 |
224325153323 |
3 |
4.4 |
High |
0 |
0.03 |
Low |
H, SA |
||
| B |
000000000003771 |
223425173563 |
13 |
19.5 |
High |
8 |
13 |
High |
H, SA |
|
| C | 677777477413771 | 254326223432 | 6 | 1.3 | Low | 3 | <0.01 | Low | FB, SA | |
| 777776777760771 |
125325153225 |
7 |
9.8 |
High |
2 |
1.8 |
High |
H, SA |
||
| D | 677777477413771 | 254326223432 | 5 | 0.8 | Low | 4 | 0.4 | Low | FB | |
| 777776757760771 |
223325143324 |
6 |
8.7 |
High |
1 |
1.2 |
Low |
|||
| E | 677777477413771 | 254326223432 | 3 | 1.0 | Low | 2 | 0.9 | Low | FB | |
*LLRs >5.0 (boldface) indicate greater possibility that the cluster represents geographically concentrated TB cases, a proxy for recent TB transmission). TB, tuberculosis; MIRU-VNTR, mycobacterial interspersed repetitive unit–variable number tandem repeat; LLR, log-likelihood ratio, a measure of geospatial concentration; H, homelessness; FB, foreign born; SA, substance abuse.
†Period 1, January 1, 2005–December 31, 2007; period 2, January 1, 2008–December 31, 2010.
‡Blank cells indicate none present.
Page created: February 01, 2013
Page updated: February 01, 2013
Page reviewed: February 01, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.