Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 19, Number 4—April 2013
CME ACTIVITY - Research

Serotype IV and Invasive Group B Streptococcus Disease in Neonates, Minnesota, USA, 2000–20101

Patricia FerrieriComments to Author , Ruth Lynfield, Roberta Creti, and Aurea E. Flores
Author affiliations: University of Minnesota Medical School, Minneapolis, Minnesota, USA (P. Ferrieri, A.E. Flores); Minnesota Department of Health, St. Paul, Minnesota, USA (R. Lynfield); Istituto Superiore di Sanità, Rome, Italy (R. Creti)

Main Article

Figure 3

DNA macrorestriction profiles for serotype IV isolates from invasive group B Streptococcus (GBS) disease in infants, Minnesota. Isolates were studied by SmaI digestion and pulsed-field gel electrophoresis (PFGE) analysis and were designated as expressing C-protein α (C-α) or group B protective surface protein (BPS). Lane number is at the top and PFGE profile number at the bottom of each lane. A) Lane 2, λ molecular size standard; lanes 3 and 4, serotype IV/C-α GBS isolates from early-onset disea

Figure 3. . . . DNA macrorestriction profiles for serotype IV isolates from invasive group B Streptococcus (GBS) disease in infants, Minnesota. Isolates were studied by SmaI digestion and pulsed-field gel electrophoresis (PFGE) analysis and were designated as expressing C-protein α (C-α) or group B protective surface protein (BPS). Lane number is at the top and PFGE profile number at the bottom of each lane. A) Lane 2, λ molecular size standard; lanes 3 and 4, serotype IV/C-α GBS isolates from early-onset disease; lanes 5–7, prototypes of PFGE profile groups 39 (IV/C-α), 38 (IV/C-α), and 37 (IV/C-α and BPS); lane 8, internal standard 89-022 (Ib/C-α and C-β). B) Lane 1, λ molecular size standard; lane 2, PFGE profile 37 prototype (IV/C-α and BPS); lanes 3–6, isolates from late-onset disease; lanes 7–9, isolates from early-onset disease; lane 10, internal standard 89-022. Protein profile of isolates in lanes 2–4, C-α and BPS; lanes 5–8, BPS only. The isolate in lane 9 did not express any of the proteins studied.

Main Article

1This work was presented in part at the XVIII Lancefield International Symposium on Streptococci and Streptococcal Diseases, September 4–8, 2011, Palermo, Italy.

Page created: March 14, 2013
Page updated: March 14, 2013
Page reviewed: March 14, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external